Results 81 to 90 of about 13,321,560 (330)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Noise Reduction Methods for Charge Stability Diagrams of Double Quantum Dots

open access: yesIEEE Transactions on Quantum Engineering, 2022
Operating semiconductor quantum dots as quantum bits requires isolating single electrons by adjusting gate voltages. The transitions of electrons to and from the dots appear as a honeycomb-like pattern in recorded charge stability diagrams (CSDs).
Sarah Fleitmann   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Psychological Effects of “Double Reduction” Policy on Students, Teachers, and Parents

open access: yesProceedings of the 2022 International Conference on Creative Industry and Knowledge Economy (CIKE 2022), 2022
The declining Chinese birth rate, the need to develop the manufacturing industry, and capital-dominated extracurricular tutoring classes that prevent the country from truly selecting innovative talents, moreover, the excessive academic burden has caused ...
Jielu Yan
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Double reduction educational policy: Impacts on grades 1-9 compulsory education in China

open access: yesInternational Journal of Chinese Education
Critical Policy Analysis (CPA) is a framework for examining policies that focuses on power, privilege, and social inequalities. Research on the impact of the Double Reduction educational policy is varied as the policy is new and may not be universally ...
Xiao Xue, Carole Makela
semanticscholar   +1 more source

Research on the Impact of China’s “Double Reduction” Policy on Out-of-School Remedial Classes

open access: yesProceedings of the 2021 3rd International Conference on Economic Management and Cultural Industry (ICEMCI 2021), 2021
Recently, the Chinese government issued a "double reduction" policy aimed at reducing the academic burden of students in the compulsory education stage. At the same time, this policy also suppressed the education industry.
Bang Wu
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Double-Layer Inhibition of Peroxydisulfate Reduction at Mercury Ultramicroelectrodes. A Quantitative Analysis of the Frumkin Effect Including Molecular Transport and Long-Range Electron Transfer

open access: yes, 2023
The electrical double layer (EDL) can lead to unexpected voltammetric phenomena. A notable example is the Frumkin effect, observed for the reduction of peroxydisulfate (S2O82–).
Henry S. White (1339506)   +1 more
core   +2 more sources

A double-suture cerclage reduction technique with Nice knots for comminuted patella fractures (AO/OTA 34-C3)

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background Comminuted patella fractures place high demands on surgeons’ surgical skills. We used a double-suture cerclage reduction with Nice knots as an intra-operative reduction technique to displaced comminuted patella fractures. Methods Patients were
Yanchun Gao   +4 more
doaj   +1 more source

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