Results 61 to 70 of about 1,416,598 (308)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Universal Quantum Computing with Spin and Valley

, 2012
We investigate a two-electron double quantum dot with both spin and valley degrees of freedom as they occur in graphene, carbon nanotubes, or silicon, and regard the 16-dimensional space with one electron per dot as a four-qubit logic space.
Burkard, Guido, Rohling, Niklas
core   +1 more source

Orlicz-Quasi-Cauchy double sequence spaces for RH-regular matrix

, 2017
In this research paper we pioneer, a new double sequence space called Orlicz-QuasiCauchy double sequence space, (M,A,Δ)OQC . We investigate continuity type properties of Orlicz double function defined on a double subset A×A of R2 into R and study some ...
K. Raj, A. Esi, S. Jamwal
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Difference Cesàro Double Sequence Space Defined by Double Orlicz Function

Journal of Physics: Conference Series, 2021
Abstract In this article, we are provide a suitable generalization of difference Cesàro double sequence spaces defined by double Orlicz functions and Study different topological properties and inclusion relationships using new kinds of double sequence spaces to generalize some known results of double Orlicz functions.
Hasan Ali Moussa, Ali Hussein Battor, Dalael Saad Abdul Zahra   +2 more
openaire   +1 more source

STATISTICAL CONVERGENCE OF DOUBLE SEQUENCES IN NEUTROSOPHIC 2-NORMED SPACES

Ural Mathematical Journal
In this paper, we have studied the notion of statistical convergence for double sequences in neutrosophic 2-normed spaces. Also, we have defined statistically Cauchy double sequences and statistically completeness for double sequences and investigated ...
Rahul Mondal, Nesar Hossain
doaj   +1 more source

Orbital order and spin-orbit coupling in BaVS3

, 2005
The correlated 3d sulphide BaVS3 undergoes a sequence of three symmetry breaking transitions which are reflected in the temperature dependence of the magnetic susceptibility, and its anisotropy.
Doniach, Inami, K. Radnóczi, Kézsmárki, Lechermann, Massenet, Mihály, P. Fazekas, Sanna, Sayetat, Yamasaki   +10 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

No evidence of chemical anomalies in the bimodal turnoff cluster NGC 1806 in the LMC

, 2014
We have studied the chemical composition of NGC 1806, a massive, intermediate-age globular cluster that shows a double main sequence turnoff. We analyzed a sample of high-resolution spectra (secured with FLAMES at the Very Large Telescope) for 8 giant ...
Dalessandro, E., Ferraro, F. R., Lanzoni, B., Mucciarelli, A., Origlia, L.   +4 more
core   +1 more source