Results 61 to 70 of about 2,897,808 (292)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Matrix transformations of double convergent sequences with powers [PDF]
In 1967, I. J. Maddox generalized the spaces c0, c, ââ by adding the powers pk (k â â) in the definitions of the spaces to the terms of elements of sequences (xk). Gökhan and Ãolak in 2004â2006 defined the corresponding double sequence spaces
Maria Zeltser, Şeyda Sezgek
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Complementary means and double sequences
We look after the complementary means with respect to a weighted geometric mean of Stolarsky means in the family of Gini means and in the family of Stolarsky means.
Gheorghe Toader
doaj
Matrix Transformations of Double Convergent Sequences with Powers for the Pringsheim Convergence
In 2004–2006, the corresponding double sequence spaces were defined for the Pringsheim and the bounded Pringsheim convergence by Gokhan and Colak. In 2009, Colak and Mursaleen characterized some classes of matrix transformations transforming the space of
Maria Zeltser, Şeyda Sezgek
doaj +1 more source
After a brief summary of Tauberian conditions for ordinary sequences of numbers, we consider summability of double sequences of real or complex numbers by weighted mean methods which are not necessarily products of related weighted mean methods in one ...
Ferenc Móricz, U. Stadtmüller
doaj +1 more source
Hankel matrices for the period-doubling sequence
We give an explicit evaluation, in terms of products of Jacobsthal numbers, of the Hankel determinants of order a power of two for the period-doubling sequence. We also explicitly give the eigenvalues and eigenvectors of the corresponding Hankel matrices. Similar considerations give the Hankel determinants for other orders.
Robbert J. Fokkink +2 more
openaire +3 more sources
Double lacunary density and lacunary statistical convergence of double sequences
In this paper, we have defined double lacunary density and investigated the relation between statistical and lacunary statistical convergence of double sequences.
Celal Çakan +5 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

