Results 51 to 60 of about 3,006,358 (252)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
DEFERRED STATISTICAL EQUIVALENCE FOR DOUBLE SEQUENCES OF SETS
, 2023 The main purpose of this paper is to introduce the concept of asymptotical deferred statistical equivalence in the Wijsman sense for double set sequences. Also, we give some properties of this concept and prove some theorems associated with this concept.
Gulle, Esra
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
On I_2-Cauchy double sequences in fuzzy normed spaces [PDF]
, 2019 In this paper, we investigate relationship between I_2-convergence and I_2-Cauchy double sequences in fuzzy normed spaces. After, we introduce the concepts of I*_2-Cauchy double sequences and study relationships between I_2-Cauchy and I*_2-Cauchy ...
Dündar, Erdinç +1 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Latest results from Double Chooz
, 2017 Double Chooz is a short-baseline neutrino disappearance experiment. It detects ν̄e produced in the power plant of Chooz, France, where is located. The main goal of the experiment is the measurement of θ13 mixing angle and in 2011 for the first time the ...
Minotti A., Double Chooz collaboration
core +1 more source
Some Spaces of Double Sequences Obtained through Invariant Mean and Related Concepts
Abstract and Applied Analysis, 2013 We introduce some double sequences spaces involving the notions of invariant mean (or -mean) and -convergence for double sequences while the idea of -convergence for double sequences was introduced by Çakan et al.
S. A. Mohiuddine, Abdullah Alotaibi
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source