Results 41 to 50 of about 3,006,358 (252)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Statistical Convergence of order ? for (?, ,?) double sequences of fuzzy numbers

open access: yes, 2020
In this study, we introduce the concepts of phi(lambda,mu)-double statistically convergence of order beta in fuzzy sequences and strongly lambda- double Cesaro summable of order beta for sequences of fuzzy numbers.
Barlak, Damla
core   +1 more source

On convergence of double sequences of functions [PDF]

open access: yes, 2014
In this work, we deal with various kinds of convergence for double sequences of functions with values in R. We introduce the concepts of uniformly convergent and uniformly Cauchy sequences for double sequences of functions and show the relation ...
Sever, Yurdal, Dündar, Erdinç
core   +1 more source

On deferred f-statistical convergence for double sequences

open access: yesOpen Mathematics
In this article, we first put forward the concept of deferred f-double natural density for double sequences, where f is an unbounded modulus. Then, we combine f-density with deferred statistical convergence for double sequences and investigate deferred f-
Zhu Yahui   +3 more
doaj   +1 more source

The X2 sequence space over p-metric spaces defined by Musielak modulus [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2014
In this paper, we introduce bonacci numbers of  2 (F) sequence space over pmetric spaces defined by Musielak function and examine some topological properties of the resulting these spaces.
Nagarajan Subramanian   +2 more
doaj  

f-asymptotically lacunary ideal equivalence of double sequences

open access: yesJournal of Inequalities and Applications, 2019
In this study, we present the notions of f-asymptotically I2 $\mathcal{I}_{2}$-equivalence, strongly f-asymptotically I2 $\mathcal{I}_{2}$-equivalence, f-asymptotically lacunary I2 $\mathcal{I}_{2}$-equivalence, and strongly f-asymptotically lacunary I2 $
Nimet Pancaroǧlu Akın
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Statistical Convergence of Double Sequences of Order

open access: yesJournal of Function Spaces and Applications, 2013
We intend to make a new approach and introduce the concepts of statistical convergence of order and strongly -Cesàro summability of order for double sequences of complex or real numbers. Also, some relations between the statistical convergence of order
R. Çolak, Y. Altin
doaj   +1 more source

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