Results 51 to 60 of about 1,889,311 (309)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Slope inequalities for fibred surfaces via GIT [PDF]
, 2008 In this paper we present a generalisation of a theorem due to Cornalba and Harris, which is an application of Geometric Invariant Theory to the study of invariants of fibrations. In particular, our generalisation makes it possible to treat the problem of
Stoppino L., Stoppino, Lidia
core +1 more source
Meikuang Anquan, 2021 In order to solve the optimization problem of internal dump and haulage system in the first mining area of Zhundong Open-pit Coal Mine, and to increase the coal production quantity and reduce the cost of internal dump and haulage system, according to ...
WANG Denglong, CHEN Tao
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Study of the time factor during one cycle of the gait on the slope [PDF]
, 1984 Time factors of walking on level ground and slopes of 3, 6, 9 and 12 degrees were studied in eight normal adult men using foot switches. The greater the inclination of the slope, the less the cadence became.
Takahashi, Hiroshi, Hiroshi TAKAHASHI
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
PLoS ONEIt is imperative to understand how foundations behave on earthen slopes to accurately predict their allowable carrying capacity in geotechnical engineering. A comprehensive finite element (FE) simulation with PLAXIS 2D was conducted to assess the effects
Khalil Sadiq Ismael +1 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
, 2011 The high density of slope failures in western Norway is due to the steep relief and to the concentration of various structures that followed protracted ductile and brittle tectonics.
I. H. C. Henderson +5 more
core +1 more source