Results 31 to 40 of about 3,201 (168)
Hemimetabolous insects elucidate the origin of sexual development via alternative splicing
eLife, 2019 Insects are the only known animals in which sexual differentiation is controlled by sex-specific splicing. The doublesex transcription factor produces distinct male and female isoforms, which are both essential for sex-specific development.
Judith Wexler +6 more
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Control of sexual differentiation and behavior by the doublesex gene in Drosophila melanogaster [PDF]
Nature Neuroscience, 2010 Doublesex proteins, which are part of the structurally and functionally conserved Dmrt gene family, are important for sex determination throughout the animal kingdom. We inserted Gal4 into the doublesex (dsx) locus of Drosophila melanogaster, allowing us to visualize and manipulate cells expressing dsx in various tissues.
Rideout, E +4 more
openaire +3 more sources
Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex
G3: Genes, Genomes, Genetics, 2016 Sex differences in gene expression have been widely studied in Drosophila melanogaster. Sex differences vary across strains, but many molecular studies focus on only a single strain, or on genes that show sexually dimorphic expression in many strains ...
Michelle N. Arbeitman +5 more
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Integrative analysis reveals pathways associated with sex reversal in Cynoglossus semilaevis [PDF]
PeerJ, 2020 Sex reversal is a complex biological phenomenon exhibited by Cynoglossus semilaevis. Some genetic females may irreversibly convert to pseudomales, thus increasing aquaculture costs because males grow much more slowly than females.
Zhan Ye +5 more
doaj +2 more sources
DoublesexEvolution Is Correlated with Social Complexity in Ants
Genome Biology and Evolution, 2018 The Dmrt (doublesex and mab-3-related transcription factor) genes are transcription factors crucial for sex determination and sexual differentiation. In some social insects, doublesex (dsx) exhibits widespread caste-specific expression across different tissues and developmental stages and has been suggested as a candidate gene for regulating division ...
Jia, L.Y. +5 more
openaire +4 more sources
The neural basis for a persistent internal state in Drosophila females
eLife, 2020 Sustained changes in mood or action require persistent changes in neural activity, but it has been difficult to identify the neural circuit mechanisms that underlie persistent activity and contribute to long-lasting changes in behavior.
David Deutsch +23 more
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Genome-wide identification and comparative analysis of Dmrt genes in echinoderms
Scientific Reports, 2023 The Dmrt (Doublesex-mab3-related transcription factor) gene family is a class of crucial transcription factors characterized by one or several conserved DM (Doublesex/Mab-3) domains.
Quanchao Wang +4 more
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European Journal of Entomology, 2018 The sex determination cascades in insects are diversified at the top of the cascade, where different primary molecular signals are employed, while at the bottom of the cascades, particularly the doublesex genes, are highly conserved.
Thanaset THONGSAIKLAING +3 more
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Nature Communications, 2020 Polymorphic mimicry in Papilio swallowtail butterflies is thought to have had multiple independent origins. Here, the authors show that the gene doublesex controls mimicry across multiple species, but with distinct alleles that may have originated from ...
Daniela H. Palmer, Marcus R. Kronforst
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Evolution of sex-specific traits through changes in HOX-dependent doublesex expression. [PDF]
PLoS Biology, 2011 Almost every animal lineage is characterized by unique sex-specific traits, implying that such traits are gained and lost frequently in evolution. However, the genetic mechanisms responsible for these changes are not understood.
Kohtaro Tanaka +4 more
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