doublesex functions early and late in gustatory sense organ development. [PDF]
PLoS ONE, 2012 Somatic sexual dimorphisms outside of the nervous system in Drosophila melanogaster are largely controlled by the male- and female-specific Doublesex transcription factors (DSX(M) and DSX(F), respectively).
David J Mellert +2 more
doaj +4 more sources
The ubiquity and ancestry of insect doublesex [PDF]
Scientific Reports, 2015 AbstractThe doublesex (dsx) gene functions as a molecular switch at the base of the insect sex determination cascade and triggers male or female somatic sexual differentiation in Drosophila. Having been reported from only seven current insect orders, the exact phylogenetic distribution of dsx within the largest Arthropod sub-phylum, the Hexapoda, is ...
Dana C. Price +2 more
openaire +2 more sources
Transgenic and knockout analyses of Masculinizer and doublesex illuminated the unique functions of doublesex in germ cell sexual development of the silkworm, Bombyx mori [PDF]
BMC Developmental Biology, 2020 Abstract Background: Masculinizer (Masc) plays a pivotal role in male sex determination in the silkworm, Bombyx mori. Masc is required for male-specific splicing of B. mori doublesex (Bmdsx) transcripts. The male isoform of Bmdsx (BmdsxM) induces male differentiation in somatic cells, while females express the female isoform of Bmdsx (BmdsxF ...
Yuzawa, Tomohisa +5 more
openaire +2 more sources
Molecular characterization of transformer, transformer-2, and doublesex genes in the carambola fruit fly, Bactrocera carambolae, revealing potential for genetic pest management. [PDF]
Insect SciAbstract Globalization and climate change may be driving the spread of the quarantine fruit fly, Bactrocera carambolae, highlighting the need for ecofriendly control methods like the Sterile Insect Technique (SIT), which relies on releasing sterile males to reduce wild populations.
Laohakieat K, Poonsiri T, Aketarawong N.
europepmc +2 more sources
Flipping the doublesex switch with a piRNA [PDF]
Genome Biology, 2014 Recent work in the silkworm Bombyx mori has uncovered a novel Piwi-interacting RNA regulator of the sex determination switch doublesex.
Whitworth, Cale, Oliver, Brian
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Constraints on the evolution of a doublesex target gene arising from doublesex’s pleiotropic deployment [PDF]
Proceedings of the National Academy of Sciences, 2015 Significance Most sexually dimorphic features of Drosophila melanogaster are specified by the action of sex-specific transcription factors encoded by the doublesex ( dsx ) gene.
Shengzhan D, Luo, Bruce S, Baker
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Double nexus--Doublesex is the connecting element in sex determination [PDF]
Briefings in Functional Genomics, 2015 In recent years, our knowledge of the conserved master-switch gene doublesex (dsx) and its function in regulating the development of dimorphic traits in insects has deepened considerably. Here, a comprehensive overview is given on the properties of the male- and female-specific dsx transcripts yielding DSX(F) and DSX(M) proteins in Drosophila ...
Verhulst, E.C., van de Zande, L.
openaire +4 more sources
Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster [PDF]
Journal of Biological Chemistry, 2008 Drosophila yolk protein genes are regulated by doublesex male protein (DSXM) in males and doublesex female protein (DSXF) in females. Both proteins bind to the same DNA sites from which DSXM represses and DSXF activates transcription. The proteins are identical through 397 NH2-terminal amino acids that include domains for oligomerization and DNA ...
Yanwu Yang +3 more
+9 more sources
Courtship Love Songs: doublesex Makes the Connection [PDF]
Developmental Cell, 2016 During courtship, Drosophila melanogaster males sing to females a song composed of rhythmic pulses and sine song. In this issue of Developmental Cell, Shirangi et al. (2016) show that a cluster of doublesex-expressing neurons directs the production of the sine song component through functional linkages to wing motoneurons.
Michelle N, Arbeitman, Nicole R, Newell
openaire +2 more sources
Identification and characterization of the doublesex gene of Nasonia [PDF]
Insect Molecular Biology, 2009 Abstract The doublesex ( dsx ) gene of the parasitic wasp Nasonia vitripennis is described and characterized.
Oliveira, D.C.S.G. +6 more
openaire +3 more sources