Results 281 to 290 of about 5,393,020 (341)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Genetic variants and down-regulation of CACNA1H in pheochromocytoma. [PDF]

open access: yesEndocr Relat Cancer
Svahn F   +14 more
europepmc   +1 more source

Surface Engineering-Induced d-Band Center Down-Regulation in High-Entropy Alloy Nanowires for Enhanced Nanozyme Catalysis. [PDF]

open access: yesAdv Sci (Weinh)
Feng K   +10 more
europepmc   +1 more source

miR-129-1-3p down-regulation promotes BAG cochaperone 3 (BAG3)-driven pro-fibrotic processes in primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. [PDF]

open access: yesNoncoding RNA Res
Nobili R   +10 more
europepmc   +1 more source

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