Results 11 to 20 of about 4,821,896 (384)

Breastfeeding in children with down syndrome. [PDF]

BMC Pediatr
Introduction Babies with Down syndrome (DS) present physical characteristics that can make breastfeeding difficult, including hypotonia of the muscles of the oral cavity and pharynx which can create problems with sucking and swallowing. Breastfeeding has
Rodríguez AO, de la Puente SG, Arizmendi KAF, Robledo TTV.   +3 more
europepmc   +2 more sources

The importance of understanding individual differences in Down syndrome [version 1; referees: 2 approved]

F1000Research, 2016
In this article, we first present a summary of the general assumptions about Down syndrome (DS) still to be found in the literature. We go on to show how new research has modified these assumptions, pointing to a wide range of individual differences at ...
Annette Karmiloff-Smith, Tamara Al-Janabi, Hana D'Souza, Jurgen Groet, Esha Massand, Kin Mok, Carla Startin, Elizabeth Fisher, John Hardy, Dean Nizetic, Victor Tybulewicz, Andre Strydom   +11 more
doaj   +2 more sources

Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome

Science Advances, 2021
Newly identified mitovesicles are a type of extracellular vesicles whose levels and cargo are altered in Down syndrome. Mitochondrial dysfunction is an established hallmark of aging and neurodegenerative disorders such as Down syndrome (DS) and Alzheimer’
Pasquale D’Acunzo, R. Pérez-González, Yohan Kim, Tal Hargash, C. Miller, M. Alldred, H. Erdjument-Bromage, Sai C. Penikalapati, M. Pawlik, M. Saito, M. Saito, S. Ginsberg, T. Neubert, C. Goulbourne, E. Levy   +14 more
semanticscholar   +1 more source

Comparison of resting-state EEG between adults with Down syndrome and typically developing controls

Journal of Neurodevelopmental Disorders, 2021
Background Down syndrome (DS) is the most common genetic cause of intellectual disability (ID) worldwide. Understanding electrophysiological characteristics associated with DS provides potential mechanistic insights into ID, helping inform biomarkers and
Sarah Hamburg, Daniel Bush, Andre Strydom, Carla M. Startin   +3 more
doaj   +1 more source

Evaluation of congenital and acquired heart diseases in a Spanish cohort of adults with Down syndrome

Scientific Reports, 2022
To describe congenital and acquired heart diseases in a Spanish cohort of adults with Down syndrome (DS), which could inform potential health recommendations for this population.
Laura Rabes, Laura Adán-Lirola, María del Pilar González-Molina, José María Galván-Román, Fernando Moldenhauer, Emilia Roy-Vallejo, Diego Real de Asúa   +6 more
doaj   +1 more source

Capturing cognitive and behavioral variability among individuals with Down syndrome: a latent profile analysis

Journal of Neurodevelopmental Disorders, 2021
Background There is a high degree of inter- and intra-individual variability observed within the phenotype of Down syndrome. The Down Syndrome Cognition Project was formed to capture this variability by developing a large nationwide database of cognitive,
M. Channell, Laura J. Mattie, D. Hamilton, G. Capone, E. M. Mahone, S. Sherman, Tracie C. Rosser, R. Reeves, Luther G. Kalb, The Down Syndrome Cognition Project   +9 more
semanticscholar   +1 more source

Lipid profile of Mexican children with Down syndrome

BMC Pediatrics, 2021
Introduction Down syndrome (DS) is associated with various congenital anomalies and metabolic alterations, such as dyslipidemias, that can lead to cardiovascular disease in adulthood.
Silvestre Garcia-de la Puente, Karla A. Flores-Arizmendi, María J. Delgado-Montemayor, Tania T. Vargas-Robledo   +3 more
doaj   +1 more source

Blood cytology in children with down syndrome

BMC Pediatrics, 2022
Introduction Down syndrome is associated with various congenital anomalies and metabolic alterations such as hematological alterations. Values for the major hematological indicators vary with age and sex, but these values have not been described for ...
Silvestre García de la Puente, Karla Adney Flores-Arizmendi, Yessica Yuliana Guerrero-Tapia, Tania Tonantzin Vargas-Robledo, Norma Candelaria López-Santiago   +4 more
doaj   +1 more source

Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer’s disease cognition

Alzheimer’s Research & Therapy, 2022
Background The apolipoprotein E (APOE) ε4 allele confers the strongest risk for late-onset Alzheimer’s disease (AD) besides age itself, but the mechanisms underlying this risk are debated.
Noah R. Johnson, Athena C.-J. Wang, Christina Coughlan, Stefan Sillau, Esteban Lucero, Lisa Viltz, Neil Markham, Cody Allen, A. Ranjitha Dhanasekaran, Heidi J. Chial, Huntington Potter   +10 more
doaj   +1 more source

The co-construction of a reading assessment measure with adults with Down syndrome: a meaningful literacy approach

Frontiers in Psychology, 2023
IntroductionThe need to develop appropriate measures of broad-based reading-related literacy skills for adults with Down syndrome has been highlighted in the literature.
Pauline Frizelle, Sean O’Donovan, Mary Jolley, Lisa Martin, Nicola Hart   +4 more
doaj   +1 more source