Results 21 to 30 of about 1,226,398 (302)
Journal of Patient-Centered Research and Reviews, 2022 Findings from a recent study of the largest documented cohort of individuals with Down syndrome (DS) in the United States described prevalence of common disease conditions and strongly suggested significant disparity in mental health conditions among ...
Anne Rivelli +6 more
doaj +1 more source
Prevalence of Endocrine Disorders Among 6078 Individuals With Down Syndrome in the United States
Journal of Patient-Centered Research and Reviews, 2022 Findings from a recent study describing prevalence of common disease conditions in the largest documented cohort of individuals with Down syndrome (DS) in the United States strongly suggested significant disparity in endocrine disorders among these ...
Anne Rivelli +6 more
doaj +1 more source
Prevalence of Infectious Diseases Among 6078 Individuals With Down Syndrome in the United States
Journal of Patient-Centered Research and Reviews, 2022 A recent disease prevalence study of the largest documented Down syndrome (DS) cohort in the United States strongly suggested significant disparity in general infectious disease conditions among individuals with DS versus those without DS. In this follow-
Veronica Fitzpatrick +6 more
doaj +1 more source
Seroconversion stages COVID19 into distinct pathophysiological states
eLife, 2021 COVID19 is a heterogeneous medical condition involving diverse underlying pathophysiological processes including hyperinflammation, endothelial damage, thrombotic microangiopathy, and end-organ damage.
Matthew D Galbraith +17 more
doaj +1 more source
A comparison between the anxiety and hope in mothers having children suffering from autism syndrome and Down syndrome [PDF]
, 2015 Introduction: The present research aimed to compare anxiety and hope between mothers having children suffering from autism syndrome and Down syndrome. Methods: This research used a descriptive-comparative method and the sample of the study included 60
Houda, Michal, Kaňková, Vlasta
core +2 more sources
Neurobiology of Disease, 2022 Down syndrome (DS) is characterized by chronic neuroinflammation, peripheral inflammation, astrogliosis, imbalanced excitatory/inhibitory neuronal function, and cognitive deficits in both humans and mouse models.
Md. Mahiuddin Ahmed +13 more
doaj +1 more source
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
Nature Communications, 2019 Down syndrome (DS) is caused by trisomy 21 (T21), but the underlying etiology of the related immune and neurological dysfunction is unclear. Here, the authors show that T21 activates the kynurenine pathway via increased interferon receptor copy number ...
Rani K. Powers +20 more
doaj +1 more source
Cell Reports, 2019 Summary: People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions.
Katherine A. Waugh +22 more
doaj +1 more source
Organoids for the Study of Retinal Development and Developmental Abnormalities
Frontiers in Cellular Neuroscience, 2021 The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these three-dimensional organoid models, in turn, have provided unprecedented opportunities for retinal ...
Anne Vielle +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source