Results 31 to 40 of about 577,319 (266)

An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21

Nature Communications
Human development involves multiple signaling pathways acting concertedly in an age- and sex-specific fashion. Trisomy 21, the genetic cause of Down syndrome, dysregulates human development leading to both early neurodevelopmental delays and atypical ...
Neetha Paul Eduthan, Micah G. Donovan, Paula Araya, Angela L. Rachubinski, Kelly D. Sullivan, Matthew D. Galbraith, Joaquin M. Espinosa   +6 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Reflections on the Quality of Life of Adults with Down Syndrome from an International Congress

Disabilities
People with Down Syndrome often experience more barriers to achieving a good quality of life compared to people without disabilities. A lot of the existing research has focused on the views of parents and professionals, rather than directly including the
Rachel Spencer, Robin Gibson, Leigh Creighton, Catherine Watson, Roy McConkey   +4 more
doaj   +1 more source

Addressing the Policy Tangle: Students with Intellectual Disability and the Path to Postsecondary Education, Employment and Community Living

Journal of Inclusive Postsecondary Education, 2019
This report examines issues regarding needed alignment of services and collaboration among agencies and institutions of higher education (IHEs) to achieve the goal of supporting youth with intellectual disability (ID) to obtain increased academic ...
Stephanie Smith Lee, Denise M. Rozell, Madeleine C. Will   +2 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Breastfeeding in children with down syndrome

BMC Pediatrics
Introduction Babies with Down syndrome (DS) present physical characteristics that can make breastfeeding difficult, including hypotonia of the muscles of the oral cavity and pharynx which can create problems with sucking and swallowing. Breastfeeding has
Alejandra Ochoa Rodríguez, Silvestre García de la Puente, Karla Adney Flores Arizmendi, Tania Tonantzin Vargas Robledo   +3 more
doaj   +1 more source

Use of the Adaptive Behaviour Dementia Questionnaire in a Down Syndrome Specialty Clinic

Journal of Integrative Neuroscience
Objective: To study the use of a dementia screening tool in our clinic cohort of adults with Down syndrome. Study Design: A retrospective chart review of patients ...
Nicolas M. Oreskovic, Ayesha Harisinghani, Caroline Bregman, Clorinda Cottrell, Margaret Pulsifer, Brian G. Skotko, Amy Torres, Alexa Gozdiff Spognardi, Stephanie L. Santoro   +8 more
doaj   +1 more source

Craniofacial features as assessed by lateral cephalometric measurements in children with Down syndrome

Progress in Orthodontics, 2016
Objective The objective of the present study is to examine the craniofacial development of patients with Down syndrome (DS) and compare them with a neurotypical population.
Veerasathpurush Allareddy, Nicholas Ching, Eric A. Macklin, Lauren Voelz, Gil Weintraub, Emily Davidson, Lisa Albers Prock, Dennis Rosen, Richard Brunn, Brian G. Skotko   +9 more
doaj   +1 more source

Down Syndrome and Parity

Public Health Genomics, 1999
<i>Objective:</i> To investigate the effect of parity on Down syndrome (DS). <i>Methods:</i> The study was conducted on data from Northeast Italy (NEI) (1981–1996) and Sicily (ISMAC) (1991–1996) Congenital Malformation Registries.
CLEMENTI, MAURIZIO, Bianca S, Benedicenti F, Tenconi R, Working Group on Down Syndrome   +4 more
openaire   +3 more sources