Results 241 to 250 of about 462,684 (373)

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Commentary: Blood metabolites as mediators in erectile dysfunction: insights from a multi-center proteomics and genetic study. [PDF]

Front Pharmacol
Huang Z, Gu H.
europepmc   +1 more source

Inhibition effects of Yuxiao San combined with cisplatin on transplanted tumor growths via upregulation of nm‑23 and downregulation of K‑ras in Lewis lung cancer mice

, 2018
Mo Tang, Shumei Wang, Yulin Wei, Jianti Fu   +3 more
openalex   +2 more sources

Lugol Increases Lipolysis through Upregulation of PPAR-Gamma and Downregulation of C/EBP-Alpha in Mature 3T3-L1 Adipocytes

, 2020
Sergio Cuellar-Rufino, Rossana C. Zepeda, Mónica Flores‐Muñoz, Santiago-Roque Isela, Omar Arroyo-Helguera   +4 more
openalex   +1 more source

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

Advanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song, Kimberly Seaman, Amel Sassi, Chun‐Yu Lin, Tiankuo Chu, Liyun Wang, Yu Sun, Lidan You   +7 more
wiley   +1 more source

Apoptosis-Related Non-Coding RNAs in Cardiac Fibrosis and Heart Failure: Implications for Pathogenesis and Therapy. [PDF]

J Inflamm Res
Wu H, Xia L, Liu C.
europepmc   +1 more source

Downregulation of ABI2 expression by EBV-miR-BART13-3p induces epithelial-mesenchymal transition of nasopharyngeal carcinoma cells through upregulation of c-JUN/SLUG signaling

, 2020
Jing Huang, You Qin, Chensu Yang, Chao Wan, Xiaomeng Dai, Yajie Sun, Jingshu Meng, Yanwei Lu, Yan Li, Zhanjie Zhang, Bian Wu, Shuangbing Xu, Honglin Jin, Kunyu Yang   +13 more
openalex   +1 more source

The gallium complex KP46 sensitizes resistant leukemia cells and overcomes Bcl-2-induced multidrug resistance in lymphoma cells via upregulation of Harakiri and downregulation of XIAP in vitro

, 2022
Nicola L. Wilke, Liliane Onambele Abodo, Corazon Frias, Jerico Frias, Jennifer Baas, Michael A. Jakupec, Bernhard K. Keppler, Aram Prokop   +7 more
openalex   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

USP14 Mediates Molecular Mechanisms Regulating Aortic Valve Stenosis Through Ubiquitination. [PDF]

J Cell Mol Med
Yang Y, Yao BC, Li JH, Chen QL, Jiang N, Wang LQ, Guo ZG.   +6 more
europepmc   +1 more source