Results 261 to 270 of about 378,928 (303)

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Long Noncoding RNAs in Aortic Dissection: Mechanistic Roles and Therapeutic Potential. [PDF]

Aging Med (Milton)
Chang C, Lan Y, Wu Z, Geng J, Guo Z, Chen Q.   +5 more
europepmc   +1 more source

Large-Pore Channels at the Maternal-Fetal Interface: Progress and Open Research Avenues. [PDF]

Biology (Basel)
Vega JL, Moral A, Gutiérrez C, Sáez JC.   +3 more
europepmc   +1 more source

AGGF1 delays endothelial cellular senescence through the TGFB3-TAK1-AMPK signaling axis. [PDF]

Biogerontology
Zhong X, Lv W, Li X, Wang L, Zhang M, Liu K, Dong J, Yuan Q, Zhang S, Wu A, Gong X, Liu J, Zhou B, Ye S, Wang Q, Xiang Y, Tian XL.   +16 more
europepmc   +1 more source

Characterization of the Immune Response of Atlantic Salmon to <i>Tenacibaculum dicentrarchi</i> Using In Vivo and In Vitro Approaches. [PDF]

Animals (Basel)
Torrealba D, Domínguez C, Valenzuela-Avilés P, Gallardo-Matus J, Mercado L, Mancilla M.   +5 more
europepmc   +1 more source

Pupil-based arousal self-regulation: impact on physiological and affective responses to emotional stimuli. [PDF]

Transl Psychiatry
Imhof J, Raschle NM, Wenderoth N, Meissner SN.   +3 more
europepmc   +1 more source

MiR-199a-3p deficiency induced by STAT3 activation drives smooth muscle cell phenotypic switching in pulmonary arterial hypertension. [PDF]

Noncoding RNA Res
He WX, Huang YJ, Ai TH, Huang SQ, You XH, Wu H, Song XW.   +6 more
europepmc   +1 more source