Results 281 to 290 of about 378,928 (303)
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Journal of Dermatological Science, 2015
Nerve growth factor (NGF), a neurotrophin that plays a critical role in developmental neurobiology, is released by proliferating keratinocytes and induces proliferation.The aim of this study was to investigate the role of tyrosine kinase receptor A (TrkA), a high-affinity receptor of NGF, in human keratinocytes.Expression of TrkA and NGF in skin ...
Sayaka, Matsumura +3 more
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Nerve growth factor (NGF), a neurotrophin that plays a critical role in developmental neurobiology, is released by proliferating keratinocytes and induces proliferation.The aim of this study was to investigate the role of tyrosine kinase receptor A (TrkA), a high-affinity receptor of NGF, in human keratinocytes.Expression of TrkA and NGF in skin ...
Sayaka, Matsumura +3 more
openaire +2 more sources
Effect of uremia on downregulation of TLR4 and upregulation of cytokines in endothelial cell
The FASEB Journal, 2017INTRODUCTION The main cause of mortality in patients with chronic kidney disease (CKD) are Cardiovascular Diseases (CVD); associated with inflammatory mechanisms, which result in endothelial dysfunction and injury.
Jacqueline Ferritto Rebello +7 more
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Molecular Biology Reports, 2013
The present study was designed to evaluate whether microRNA-146a and its adapter proteins (TRAF6 and IRAK1) are involved in the pathogenesis of diabetes-induced kidney damage. Male Sprague-Dawley rats were divided into control and diabetic groups (n = 6 in each).
Mohammad Reza, Alipour +4 more
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The present study was designed to evaluate whether microRNA-146a and its adapter proteins (TRAF6 and IRAK1) are involved in the pathogenesis of diabetes-induced kidney damage. Male Sprague-Dawley rats were divided into control and diabetic groups (n = 6 in each).
Mohammad Reza, Alipour +4 more
openaire +2 more sources
International Archives of Allergy and Immunology, 1999
We examined the level of expression of CD11b on eosinophils in pripheral blood samples from patients with atopic dermatitis (AD) and non-AD volunteers. Eosinophils were defined using a new method employing CD14/CD45 and a backgate technique. Overexpression of CD11b was noted in eosinophils of AD patients.
H, Yamada +5 more
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We examined the level of expression of CD11b on eosinophils in pripheral blood samples from patients with atopic dermatitis (AD) and non-AD volunteers. Eosinophils were defined using a new method employing CD14/CD45 and a backgate technique. Overexpression of CD11b was noted in eosinophils of AD patients.
H, Yamada +5 more
openaire +2 more sources
Rat model of constutional upregulation/downregulation of the serotonin transporter
2002The serotonin transporter (5HTt) regulates 5HT transmission by reuptake of the amine into the presynaptic terminal. Its malfunction has been linked to etiopathogenesis of several neuropsychiatric disorders and it also represents a target for SRI antidepressants.
Jernej, Branimir +4 more
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Journal of Cellular Physiology, 2018
AbstractMembranous glomerulonephropathy (MGN) is a glomerulopathy characterized by subepithelial deposits of immune complexes on the extracapillary side of the glomerular basement membrane. Insertion of C5b‐9 (complement membrane‐attack complex) into the membrane leads to functional impairment of the glomerular capillary wall.
Barbagallo, Cristina +14 more
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AbstractMembranous glomerulonephropathy (MGN) is a glomerulopathy characterized by subepithelial deposits of immune complexes on the extracapillary side of the glomerular basement membrane. Insertion of C5b‐9 (complement membrane‐attack complex) into the membrane leads to functional impairment of the glomerular capillary wall.
Barbagallo, Cristina +14 more
openaire +4 more sources
SUN2 downregulation promotes breast cancer cell proliferation via NFATC4 upregulation
Biochemical and Biophysical Research CommunicationsThe linker of nucleoskeleton and cytoskeleton (LINC) complex component Sad1/UNC-84 domain-containing protein 2 (SUN2) is essential for maintaining nuclear envelope integrity and mechanical signaling between the cytoskeleton and the nucleus. However, its functional significance in breast cancer remains unclear.
Jaehyeok Lee +9 more
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Plant Growth Regulators and Secondary Metabolites, Downregulation and Upregulation
2021openaire +1 more source