Results 121 to 130 of about 360,193 (299)

Influences of Body Size and Environmental Factors on Autumn Downstream Migration of Bull Trout in the Boise River, Idaho

open access: yes, 2008
Many fishes migrate extensively through stream networks, yet patterns are commonly described only in terms of the origin and destination of migration (e.g., between natal and feeding habitats).
Peter Koetsier   +7 more
core   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

open access: yesAdvanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim   +9 more
wiley   +1 more source

Darkness represses the onset of downstream migration in hatcheryreleased chum salmon, Oncorhynchus keta, fry

open access: yes, 2007
Downstream migration and plasma thyroxine (T4) levels in hatchery reared chum salmon, Oncorhynchus keta, fry were investigated late in the migration season.
OJIMA Daisuke   +2 more
core  

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Anadromy in Fragmented Rivers: Downstream Passage Challenges for Migrating Salmonids

open access: yes
Migration is essential for anadromous salmonids; however, hydropower electric power (HEP) development has fragmented rivers and disrupted downstream passage for juveniles (smolts) and adults (kelts), delaying migration and increasing mortality.
openaire   +2 more sources

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

open access: yesAdvanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao   +9 more
wiley   +1 more source

KRAS downstream pathway, adhesion and migration in EGF-treated cells.

open access: yes, 2015
A. Downstream targets of KRAS signaling pathway were analyzed by western blot to determine pAKT and pERK1/2 levels after EGF-treatment. B. Cell adhesion was determined by western blot analysis of TALIN cleavage in HAF1 and HAE6 cells. C.
Luís Franco (5664148)   +11 more
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Channel Confinement Drives Unidirectional Migration: Coupling of Flow Structure and Sedimentary Evolution in Combined Turbidity–Bottom Current Flows

open access: yesJournal of Marine Science and Engineering
Along-slope bottom currents and down-slope (gravity-driven) turbidity currents coexist in the ocean and interact during their flow processes. The interaction between turbidity currents and bottom currents plays a crucial role in determining the lateral ...
Renqian Zhang   +7 more
doaj   +1 more source

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