Results 81 to 90 of about 596,534 (308)

Natural attenuation of Fukushima-derived radiocesium in soils due to its vertical and lateral migration [PDF]

, 2018
Processes of vertical and lateral migration lead to gradual reduction in contamination of catchment soil, particularly its top layer. The reduction can be considered as natural attenuation.
Carradine, M., Cresswell, A., Golosov, V., Ivanov, M., Konoplev, A., Nanba, K., Onda, Y., Parenyuk, O., Takase, T., Wakiyama, Y., Yoschenko, V., Yoshihara, T.   +11 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Evolution of focused streams for viscoelastic flow in spiral microchannels

Microsystems & Nanoengineering, 2023
Particle migration dynamics in viscoelastic fluids in spiral channels have attracted interest in recent years due to potential applications in the 3D focusing and label-free sorting of particles and cells.
Hua Gao, Jian Zhou, Mohammad Moein Naderi, Zhangli Peng, Ian Papautsky   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Predation risk in stocking programs: case study on a critically endangered diadromous species, the European sturgeon Acipenser sturio

Frontiers in Marine Science
Juveniles produced in hatcheries for stocking purposes can have compromised behavior compared to wild conspecifics, especially concerning inappropriate anti-predator responses.
Marie-Laure Acolas, Jérémy Tourneur, Thibault Dindart, Frédérique Bau, François Druyer, Bénédicte Lalot, Coralie Roy-Camille, Florent Lalanne, Vanessa Lauronce, Géraldine Loot, Géraldine Loot   +10 more
doaj   +1 more source

Observations on the downstream movements of brown trout fry (Salmo trutta L.)in the Lissuraga [Translation from: Bulletin Francais de la Pisciculture No.274 1-17, 1979] [PDF]

, 1980
The phenomenon of the downstream movement of brown trout fry has been noticed for a very long time by fish biologists. The work presented here, and taking place in the framework of the hydrobiological research of the INRA, represents the results of three
Cuinat, R., Heland, M.
core  

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib [PDF]

Journal of Cell Biology, 2016
Semaphorins comprise a large family of ligands that regulate key cellular functions through their receptors, plexins. In this study, we show that the transmembrane semaphorin 4A (Sema4A) can also function as a receptor, rather than a ligand, and transduce signals triggered by the binding of Plexin-B1 through reverse signaling.
Tianliang Sun, Lida Yang, Harmandeep Kaur, Jenny Pestel, Mario Looso, Hendrik Nolte, Cornelius Krasel, Daniel Heil, Ramesh K. Krishnan, Marie-Josée Santoni, Jean-Paul Borg, Moritz Bünemann, Stefan Offermanns, Jakub M. Swiercz, Thomas Worzfeld   +14 more
openaire   +4 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Myosin II governs collective cell migration behaviour downstream of guidance receptor signalling [PDF]

Journal of Cell Science, 2016
Border cell migration during Drosophila oogenesis is a potent model to study collective cell migration, a process involved in development and metastasis. Border cell clusters adopt two main types of behaviour during migration: linear and rotational. Still, the molecular mechanism controlling the switch from one to the other is unknown.
Anne Combedazou, Valérie Choesmel-Cadamuro, Guillaume Gay, Jiaying Liu, Loïc Dupré, Damien Ramel, Xiaobo Wang   +6 more
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source