Results 61 to 70 of about 596,534 (308)
Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. [PDF]
, 2015 In glioblastoma (GBM), the EGF receptor (EGFR) and Src family kinases (SFKs) contribute to an aggressive phenotype. EGFR may be targeted therapeutically; however, resistance to EGFR-targeting drugs such as Erlotinib and Gefitinib develops quickly.
Cavenee, WK +5 more
core
AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins [PDF]
, 2017 The purpose of this study was to elucidate the mechanisms associated with the specific effects of AKT1 and AKT2 isoforms in breast cancer progression. We modulated the abundance of specific AKT isoforms in IBH-6 and T47D human breast cancer cell lines ...
Abba, Martín Carlos +7 more
core +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Известия ТИНРОVariability of the timing for downstream migration of juvenile pink salmon from the Hailulya River to the adjacent coastal waters of Karaginsky Bay is considered and influence of the coastal water temperature on strength of the year-classes for two ...
Е. А. Shevlyakov +3 more
doaj +1 more source
Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway
BMC Cancer, 2021 Background UEV1A encodes a ubiquitin-E2 variant closely associated with tumorigenesis and metastasis, but its underlying mechanism in promoting metastasis remains to be investigated.
Tong Niu, Zhaojia Wu, Wei Xiao
doaj +1 more source
Insights into Daily Dynamics of Fish Migration during Spring in the Konda River
Diversity, 2023 Hydrology and temperature are known as key drivers for fish migration in floodplain-channel systems of large rivers. The Lower Irtysh contains valuable species of whitefish and sturgeon.
Andrey A. Chemagin, Martin Schletterer
doaj +1 more source
Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]
, 2013 Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Plate, Karl H. +2 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Knowledge and Management of Aquatic Ecosystems, 1999 Une expérimentation a été conduite en 1996 au niveau de l'aménagement hydroélectrique de St. Cricq (gave d'Ossau) dans le but de tester deux dispositifs de dévalaison destinés à éviter le passage dans les turbines des smolts de saumon atlantique (Salmo ...
TRAVADE F., GOUYOU C., DE FAVERI N.
doaj +1 more source
BMC Cancer, 2011 Background Recently it has been shown that radiation induces migration of glioma cells and facilitates a further spread of tumor cells locally and systemically. The aim of this study was to evaluate whether radiotherapy induces migration in head and neck
Schlegel Jürgen +11 more
doaj +1 more source