Results 51 to 60 of about 596,534 (308)

Back-flow ripples in troughs downstream of unit bars: Formation, preservation and value for interpreting flow conditions [PDF]

, 2015
Back-flow ripples are bedforms created within the lee-side eddy of a larger bedform with migration directions opposed or oblique to that of the host bedform.
Allen J.R.L., Allen J.R.L., Allen J.R.L., Allen J.R.L., Best J., Boersma J.R., De Mowbray T., Gradzinski R., Gustavson T.C., Harms J.C., Hunter R.E., Jopling A.V., Jopling A.V., Martinius A.W., McCabe P.J., Nezu I., Reesink A.J.H., Tillman R.W., Van den Berg J.H., Yalin M.S.   +19 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Thermal regime of coastal waters and possible mechanisms of formation for strong year-classes of West Kamchatka pink salmon

Известия ТИНРО
Dynamics of downstream migration is considered for juvenile pink salmon at West Kamchatka in 1975–2023. Lengthening of the migration period is noted for recent years with high parental stocks.
N. A. Dederer, E. A. Shevlyakov, S. V. Naydenko   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Results of the count of juvenile pink salmon Oncorhynchus gorbuscha in the Malaya Khuzi River (Sakhalin Island) in 2022–2024

Известия ТИНРО
Migration of juvenile pink salmon Oncorhynсhus gorbuscha in the Malaya Khuzi River (northeastern Sakhalin Island) was studied in May-July of 2022, 2023 and 2024.
A. N. Elnikov, A. A. Zhivoglyadov, О. V. Zelennikov   +2 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

SUIVI DE LA MIGRATION D’AVALAISON DES ANGUILLES PAR UNE CONDUITE DE DEBIT RESERVE

Knowledge and Management of Aquatic Ecosystems, 2003
Le suivi de la migration catadrome de l’anguille par une conduite de débit réservé a été réalisé sur le barrage de la retenue de Bois Joli sur le Frémur (dénivelé : 13,7 m ; 3 millions de m3). Une partie des migrateurs utilise cette conduite, au début de
LEGAULT A., ACOU A., GUILLOUËT J., FEUNTEUN E.   +3 more
doaj   +1 more source

The anatomy of exhumed river-channel belts: Bedform to belt‐scale river kinematics of the Ruby Ranch Member, Cretaceous Cedar Mountain Formation, Utah, USA [PDF]

, 2020
Many published interpretations of ancient fluvial systems have relied on observations of extensive outcrops of thick successions. This paper, in contrast, demonstrates that a regional understanding of palaeoriver kinematics, depositional setting and ...
Cardenas, Benjamin T., Goudge, Timothy A., Hughes, Cory M., Levy, Joseph S., Mason, Jasmine, Mohrig, David, Swanson, Travis, Zhao, Feifei   +7 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

La dévalaison des migrateurs : problèmes et dispositifs

Knowledge and Management of Aquatic Ecosystems, 1999
Cet article, qui actualise le chapitre 13 du n°326-327 du Bulletin Français de la Pêche et de la Pisciculture des mêmes auteurs, fait le bilan des connaissances actuelles sur la migration de dévalaison au niveau des centrales hydroélectriques, que ce ...
LARINIER M., TRAVADE F.
doaj   +1 more source