Results 121 to 130 of about 413,339 (385)

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah, Yu Qin, Mark A. Green, James D. E. T. Wilton‐Ely   +3 more
wiley   +1 more source

Comparison of carboplatin and doxorubicin-based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma. [PDF]

, 2014
BackgroundMany chemotherapy protocols have been reported for treatment of canine appendicular osteosarcoma (OSA), but outcome comparisons in a single population are lacking.ObjectiveTo evaluate the effects of protocol and dose intensity (DI) on treatment
Burton, JH, Lana, SE, Selmic, LE, Thamm, DH, Withrow, SJ   +4 more
core   +2 more sources

Doxorubicin pharmacokinetics in lymphoma patients treated with doxorubicin-loaded eythrocytes

Haematologica, 2007
Doxorubicin-loaded erythrocytes (DLE) were administrated to 15 lymphoma patients. Antibiotic peak concentration in blood decreased by 55%, doxorubicin circulated several times longer, and the area under the concentration-time curve increased 5 times if compared with standard doxorubicin administration. The DLE was well tolerated by patients.
Skorokhod, Oleksii, Kulikova, Elena V, Galkina, Ninel M, Medvedev, Pavel V, Zybunova, Elena E, Vitvitsky, Victor M, Pivnik, Aleksandr V, Ataullakhanov, Fazoil I   +7 more
openaire   +6 more sources

Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model

BMC Cancer, 2019
Doxorubicin is currently the most effective chemotherapeutic drug used to treat breast cancer. It has, however, been shown that doxorubicin can induce drug resistance resulting in poor patient prognosis and survival. Studies reported that the interaction
C. Christowitz, T. Davis, A. Isaacs, G. van Niekerk, S. Hattingh, A. Engelbrecht   +5 more
semanticscholar   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Prospective Phase II trial of drug-eluting bead chemoembolization for liver transplant candidates with hepatocellular carcinoma and marginal hepatic reserve. [PDF]

, 2019
Purpose: To determine whether chemoembolization using drug-eluting beads (DEB-TACE) is safe and effective for liver transplantation candidates with liver-limited hepatocellular carcinoma (HCC) without vascular invasion and baseline hepatic dysfunction ...
Fidelman, Nicholas, Johanson, Curt, Kelley, R Kate, Kerlan, Robert K, Kohi, Maureen P, Kohlbrenner, Ryan M, Kolli, K Pallav, Lehrman, Evan D, Roberts, John P, Taylor, Andrew G, Yao, Francis Y   +10 more
core   +1 more source

Owner perceptions of their cat's quality of life when treated with a modified University of Wisconsin-Madison protocol for lymphoma [PDF]

, 2017
The objectives of this study were to assess owner perceptions of their cat’s quality of life during treatment for lymphoma with a doxorubicin-containing multi-agent chemotherapy protocol, whether various health-related parameters correlated with quality ...
Anneliese J Stell, Dorn CR, Hill M, Janis P Bridges, Laura A Thornton, Michael M, Nicholas Cave, Slater MR   +7 more
core   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Epirubicin. A new entry in the list of fetal cardiotoxic drugs? Intrauterine death of one fetus in a twin pregnancy. Case report and review of literature [PDF]

, 2015
BACKGROUND: Current knowledge indicate that epirubicin administration in late pregnancy is almost devoid of any fetal cardiotoxicity. We report a twin pregnancy complicated by breast cancer in which epirubicin administration was causatively linked to ...
BRUNELLI, Roberto, CASCIALLI, Gian Luca, DERME, MARTINA, FRAMARINO DEI MALATESTA, Marialuisa, GALOPPI, Paola, GIANCOTTI, Antonella, IANNINI, ISABELLA, PERRONE, Giuseppina, SAMMARTINO, Paolo, TIBALDI, VALENTINA, VENTRIGLIA, Flavia   +10 more
core   +2 more sources

NADPH oxidase 2 mediates cardiac sympathetic denervation and myocyte autophagy, resulting in cardiac atrophy and dysfunction in doxorubicin-induced cardiomyopathy

Scientific Reports
Doxorubicin has been used extensively as a potent anticancer agent, but its clinical use is limited by its cardiotoxicity. However, the underlying mechanisms remain to be fully elucidated.
Yuan Ma, Hui-Ping Zhao, Li-Guo Yang, Lu Li, Ai-Lin Wang, Xiao-Juan Zhang, Ke Wang, Bin Yang, Zong-Feng Zhu, Pei-Jun Zhang, Jia-Pu Wang, Rui-Fang Chi, Bao Li, Fu-Zhong Qin, Zhi-Peng Wang   +14 more
doaj   +1 more source