Results 131 to 140 of about 397,699 (411)
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise [PDF]
, 2011 The mechanism of chemotherapy-induced acceleration of ovarian aging is not fully understood. We used doxorubicin, a widely used cancer chemotherapeutic, in a variety of in vivo xenograft, and in vitro models to investigate the impact of chemotherapy ...
Darzynkiewicz, Zbigniew +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Archives of Pharmacy Practice, 2016 Cancer remains a major cause of hospitalization and death every year. From time to time, new formulations of anticancer drugs are available in the market and draw the concern of healthcare professionals in terms of the superiority, toxicology, and cost ...
Yik Hoe Ngan, Manish Gupta
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A hollow‐structured Fe3O4@AgAu@PDA‐ZnPc nanosphere has been developed, exhibiting controllable catalytic activity and “photothermal‐photodynamic‐Ag+” coupling antibacterial characteristics. When subjected to a rotating magnetic field, these performances are uniquely enhanced by magnetic propulsion, allowing the nanosphere to function as a magnetic ...
Jing Wang +7 more
wiley +1 more source
Owner perceptions of their cat's quality of life when treated with a modified University of Wisconsin-Madison protocol for lymphoma [PDF]
, 2017 The objectives of this study were to assess owner perceptions of their cat’s quality of life during treatment for lymphoma with a doxorubicin-containing multi-agent chemotherapy protocol, whether various health-related parameters correlated with quality ...
Anneliese J Stell +7 more
core +1 more source
BMC Cancer, 2019 Doxorubicin is currently the most effective chemotherapeutic drug used to treat breast cancer. It has, however, been shown that doxorubicin can induce drug resistance resulting in poor patient prognosis and survival. Studies reported that the interaction
C. Christowitz +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Variable Response to Chemotherapeutics by a Subpopulation of MCF-7 Breast Cancer Cells [PDF]
, 2016 Several different morphologies can be observed in a population of MCF-7 breast cancer cells, but the typical epithelial morphology vastly predominates. After treatment with the chemotherapeutic doxorubicin, the proportion of abnormal morphologies greatly
Dorland, Julie
core +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source