Results 171 to 180 of about 413,339 (385)

Effect of Eight Weeks of Interval Training Combined with Curcumin Consumption on Cardiac ERK1/2, PI3k and IL-18 Levels in Rats with Breast Cancer Treated with Doxorubicin [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Doxorubicin increases oxidative stress and cardiac damage. ERK1/2, PI3k, and IL-18 seem to play an important role in increasing cardiac damage.
Narges Laghaei, Sedigheh HosseinpourDelavar, Mehran Ghahramani   +2 more
doaj  

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten   +7 more
wiley   +1 more source

A Pegylated Liposomal Platform: Pharmacokinetics, Pharmacodynamics, and Toxicity in Mice Using Doxorubicin as a Model Drug

Journal of Pharmacological Sciences, 2004
Aims were to observe pharmacokinetics, pharmacodynamics, and toxicity for constructing a Sino-pegylated liposomal platform. Human hepatocarcinoma cells (Bel7402) and murine hepatocarcinoma cells (H22) were used for the cytotoxicity assay and the in vivo ...
Wan-Liang Lu, Xian-Rong Qi, Qiang Zhang, Rong-Yu Li, Gui-Lin Wang, Rui-Juan Zhang, Shu-Li Wei   +6 more
doaj  

Cardiomyocyte-specific knockout of ADAM17 alleviates doxorubicin-induced cardiomyopathy via inhibiting TNFα–TRAF3–TAK1–MAPK axis

Signal Transduction and Targeted Therapy
The pathogenesis of doxorubicin-induced cardiomyopathy remains unclear. This study was carried out to test our hypothesis that ADAM17 aggravates cardiomyocyte apoptosis induced by doxorubicin and inhibition of ADAM17 may ameliorate doxorubicin-induced ...
Lin Xie, Fei Xue, Cheng Cheng, Wenhai Sui, Jie Zhang, Linlin Meng, Yue Lu, Wenjing Xiong, Peili Bu, Feng Xu, Xiao Yu, Bo Xi, Lin Zhong, Jianmin Yang, Cheng Zhang, Yun Zhang   +15 more
doaj   +1 more source

Bioengineered Models of Nerve Regeneration

Advanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson, John Paul Frampton   +1 more
wiley   +1 more source

Pharmacokinetics of Doxorubicin in Man with Induced Acid or Alkaline Urine [PDF]

, 1988
Anders Krarup‐Hansen, Karsten Wassermann, S. N. Rasmussen, M. Dalmark   +3 more
openalex   +1 more source

Fluorescence Label‐Free Doxorubicin Sensor Using Polystyrene Sulfonate as a Synthetic Receptor in Whispering Gallery Mode Microresonators

Advanced Sensor Research, EarlyView.
The illustration showcases resonant optical microsensors for Doxorubicin (DXR) detection, using polystyrene sulfonate (PSS) as a synthetic receptor. PSS is deposited as a nanometer‐thick layer on fluorescent microparticles via layer‐by‐layer assembly. DXR‐PSS interaction is depicted, highlighting its effect on the sensor's resonant modes.
Elena Maurina, Algı Domac, Mateusz Olszyna, Lars Dähne, Giuseppe Barillaro   +4 more
wiley   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Risk factors of doxorubicin-induced cardiomyopathy in non-muscle- invasive bladder cancer

Universa Medicina
Background Doxorubicin is an anthracycline antibiotic widely used as a chemotherapeutic agent to treat solid tumors and hematologic malignancies.
I Made Nugraha Gunamanta Sabudi, Ahmad Zulfan Hendri   +1 more
doaj   +1 more source

Recombinant Interferon Alfa-2b Combined with a Regimen Containing Doxorubicin in Patients with Advanced Follicular Lymphoma [PDF]

, 1993
Philippe Solal‐Céligny, Éric Lepage, Nicole Brousse, Félix Reyes, Corinne Haïoun, M Leporrier, Michel Peuchmaur, André Bosly, Y Parlier, Pauline Brice, Bertrand Coiffier, Christian Gisselbrecht   +11 more
openalex   +1 more source