Results 211 to 220 of about 413,339 (385)

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

Nature Network Boston, 2016
P. Burridge, Y. F. Li, Elena Matsa, Haodi Wu, S. Ong, Arun Sharma, Alexandra Holmström, Alex C. Y. Chang, Michael Coronado, Antje D. Ebert, J. Knowles, M. Telli, R. Witteles, H. Blau, D. Bernstein, R. Altman, Joseph C. Wu   +16 more
semanticscholar   +1 more source

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

Doxorubicin-Induced Cardiotoxicity: A Comprehensive Update. [PDF]

J Cardiovasc Dev Dis
Bhutani V, Varzideh F, Wilson S, Kansakar U, Jankauskas SS, Santulli G.   +5 more
europepmc   +1 more source

Etoposide, cyclophosphamide, cisplatin, and doxorubicin as neoadjuvant chemotherapy for osteosarcoma [PDF]

, 1991
William F. Cassano, John Graham‐Pole, Nancy Dickson   +2 more
openalex   +1 more source

Targeted Dual‐Responsive Liposomes Co‐Deliver Jolkinolide B and Ce6 to Synergistically Enhance the Photodynamic/Immunotherapy Efficacy in Gastric Cancer through the PANoptosis Pathway

Advanced Science, EarlyView.
Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma, Lei Gao, Kewei Song, Baohong Gu, Bofang Wang, Yang Yu, Xueyan Wang, Xuemei Li, Jike Hu, Weigao Pu, Yunpeng Wang, Na Wang, Dedai Lu, Zhijian Han, Hao Chen   +14 more
wiley   +1 more source

Effects of Dulaglutide in Doxorubicin Induced Renal Toxicity in Rats. [PDF]

Biologics
Hama Said HJ, Ahmed ZA.
europepmc   +1 more source

Synthesis and antileukemic activity of N-enamine derivatives of daunorubicin, 5-iminodaunorubicin, and doxorubicin.

, 1988
Barbara Stefańska, M. DZIEDUSZYCKA, Maria M. Bontemps‐Gracz, E. Borowski, Sante Martelli   +4 more
openalex   +2 more sources

Doxorubicin: The dogma and the bone

Asian Journal of Pharmaceutical Sciences, 2016
Wong, J., Sriamornsak, P., Dass, Crispin
openaire   +4 more sources

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

Extravascular leakage of dexrazoxane that occurred in a patient with diffuse large B-cell lymphoma: a case report. [PDF]

J Pharm Health Care Sci
Wakamiya N, Suzuki M, Isezaki T, Funakoshi R.   +3 more
europepmc   +1 more source