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Ubiquitination in cancer: mechanisms and therapeutic opportunities
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu+7 more
wiley +1 more source
Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer. [PDF]
Schreiber AR+8 more
europepmc +1 more source
Case Report: A dual challenge: navigating cardiac leiomyosarcoma and benign pulmonary mass. [PDF]
Wu S+6 more
europepmc +1 more source
Real-world survival outcomes and MDM2 prevalence in US patients with metastatic dedifferentiated liposarcoma. [PDF]
Robinson S+4 more
europepmc +1 more source
Protective effects of Aloe vera extract against doxorubicin-induced degeneration in ovarian follicles and stromal cells in mice. [PDF]
Assis EIT+10 more
europepmc +1 more source
Charting the regulatory landscape of TP53 on transposable elements in cancer. [PDF]
Qu X+9 more
europepmc +1 more source
Dexrazoxane makes doxorubicin-induced heart failure a rare event in sarcoma patients receiving high cumulative doses. [PDF]
Zheng H, Zhan H.
europepmc +1 more source