Results 121 to 130 of about 167,098 (312)
637. Intrathecal Electroporation of Doxycycline Regulated Proopiomelanocortin Gene for the Neuropathic Pain Therapy in CCI Rats [PDF]
openalex +1 more source
Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]
microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha +4 more
core
Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions
Shake flask cultures of psilocybin‐producing A. nidulans were investigated with respect to nitrogen source, rheology, power input, and oxygen availability, and subsequently scaled to a stirred tank reactor scale based on specific power input to develop and optimize a pressurized bioprocess.
Sophie Weiser +7 more
wiley +1 more source
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui +7 more
wiley +1 more source
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang +11 more
wiley +1 more source
Skeletal Muscle PGC-1β Signaling is Sufficient to Drive an Endurance Exercise Phenotype and to Counteract Components of Detraining in Mice [PDF]
Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α and -1β serve as master transcriptional regulators of muscle mitochondrial functional capacity and are capable of enhancing muscle endurance when overexpressed in mice.
Ayala, Julio +8 more
core +1 more source
Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo +9 more
wiley +1 more source
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
Chlorogenic acid attenuates tet (X)-mediated doxycycline resistance of Riemerella anatipestifer
IntroductionThe increasing resistance of R. anatipestifer has posed a significant threat to the poultry industry in recent years. The tet gene is the primary determinant of tetracycline resistance in numerous bacteria, and the enzyme modification gene ...
Yuwen Han +6 more
doaj +1 more source

