Results 161 to 170 of about 159,147 (288)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Concentrations of selected antimicrobials in caecum, colon and manure of pigs due to a 3% cross-contamination of the feed and their effect on resistance in Escherichia coli [PDF]

open access: yes, 2015
Butaye, Patrick   +8 more
core  

Risk of infection in dogs in contact with clinical canine leptospirosis cases

open access: yesAustralian Veterinary Journal, EarlyView.
Background and aim Canine leptospirosis cases have been increasing since the disease emerged in urban Sydney in 2017. Clinical infection is associated with a high case fatality rate and might pose public health risks. This study was conducted to determine whether Leptospira spp.
VJ Skinner, MP Ward, C Griebsch
wiley   +1 more source

Effectiveness of Doxycycline in Combination With Other Antibiotics for Gram-Positive Periprosthetic Joint Infections: A Causal Inference Study. [PDF]

open access: yesOpen Forum Infect Dis
Godon J   +12 more
europepmc   +1 more source

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

open access: yesAustralian Veterinary Journal, EarlyView.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley   +1 more source

Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan Modulators. [PDF]

open access: yesAging Cell
Lalou A   +15 more
europepmc   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Suspected doxycycline-induced thrombocytopenia: Two case reports and a review of the literature. [PDF]

open access: yesMedicine (Baltimore)
Ling F   +9 more
europepmc   +1 more source

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