Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Doxycycline-Induced Phototoxicity Localized to Vitiligo-Affected and Sun-Exposed Skin. [PDF]
Dong S, Harris C, Ly A, Lee PS.
europepmc +1 more source
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Constitutive AMPK activation prevents hepatocellular carcinoma development through inhibition of HNF4α activity. [PDF]
Sun Z +6 more
europepmc +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Timing and efficacy of doxycycline in macrolide-resistant <i>Mycoplasma pneumoniae</i> pneumonia in children: a single-center retrospective study. [PDF]
Liu S, Zhang L, Dai L, Li D.
europepmc +1 more source
Concentrations of selected antimicrobials in caecum, colon and manure of pigs due to a 3% cross-contamination of the feed [PDF]
Butaye, Patrick +7 more
core
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes +2 more
wiley +1 more source
Monotherapy is Recommended in the Treatment of Scrub Typhus and Doxycycline Resistance is a Misconception [PDF]
Abheek Sil +2 more
doaj +1 more source

