On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity
Abstract Background The shape of cell survival curves at the tissue level remains an open question in radiobiology. While homogeneous cell populations (so‐called single cells) typically exhibit an exponential decrease in survival with increasing dose, it is unclear whether this behavior persists in multicellular systems, where oxygen and nutrient ...
Uwe Schneider +2 more
wiley +1 more source
Organ Transplantation: Current Status, Challenges, and Future Prospects
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
Simulated Abrupt Shifts in Aerobic Habitats of Marine Species in the Past, Present, and Future
Abstract The physiological tolerances of marine species toward ambient temperature and oxygen can jointly be evaluated in a single metric: the metabolic index. Changes therein characterize a changing aerobic habitat tailored to species‐specific thermal and hypoxia sensitivity traits. If the geographical limits of marine species as indicated by critical
Friederike Fröb +4 more
wiley +1 more source
Functions of Orc1-2 in the DNA damageresponsive regulation in Sulfolobus islandicus
Archaea constitutes the third domain of life. Comparative genomic analyses have revealed that the archaeal DNA replication machinery shares similarity with that of eukaryotes and can generally be considered a simplified version of the eukaryotic ...
Sun, Mengmeng
core +1 more source
Effect of Hypoxic Blood Infusion on Pulmonary Physiology. [PDF]
Pittman RN, Yoshida T, Omert LA.
europepmc +1 more source
Translational evaluation of gait behavior in rodent models of arthritic disorders with the CatWalk device - a narrative review. [PDF]
Ritter J +7 more
europepmc +1 more source
Dissection of Functional Domains of Orc1-2, the Archaeal Global DNA Damage-Responsive Regulator. [PDF]
Liu X +6 more
europepmc +1 more source
Ex Vivo Lung Perfusion with β-Nicotinamide Adenine Dinucleotide (NAD+) Improves Ischemic Lung Function. [PDF]
Ehrsam JP +5 more
europepmc +1 more source
The application of data altruism in clinical research through empirical and legal analysis lenses. [PDF]
Lalova-Spinks T, Meszaros J, Huys I.
europepmc +1 more source
Modeling dynamic oxygen permeability as a mechanism to mitigate oxygen-induced stresses on photosynthesis and N<sub>2</sub> fixation in marine <i>Trichodesmium</i>. [PDF]
Luo W +4 more
europepmc +1 more source

