Results 91 to 100 of about 183,863 (245)

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]

, 2017
Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins, Amélia P. Rauter, Andreia Lopes, Bhandari U, Huang X, José M. F. Nogueira, João Varela, Kilinc M, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Muriach M, Nishishiro M, Nuno R. Neng, Shai LJ, Veerasamy R   +16 more
core   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Antioxidant, Anti-Nephrolithe Activities and in Vitro Digestibility Studies of Three Different Cyanobacterial Pigment Extracts

Marine Drugs, 2015
Phycobiliprotein-containing water and carotenoid-containing methanolic extracts of three different cyanobacteria, Pseudanabaena sp., Spirulina sp. and Lyngbya sp., were studied for their DPPH scavenging, iso-bolographic studies, and anti-nephrolithe ...
Chetan Paliwal, Tonmoy Ghosh, Khushbu Bhayani, Rahulkumar Maurya, Sandhya Mishra   +4 more
doaj   +1 more source

Kinetic study of pilot-scale supercritical CO2 extraction of rosemary (Rosmarinus officinalis) leaves [PDF]

, 2011
NOTICE: This is the author’s version of a work that was accepted for publication in Journal of Supercritical Fluids. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Fornari, Tiziana, García-Risco, Mónica, Hernández, Elvis J., Reglero, Guillermo, Señoráns Rodríguez, Francisco Javier, Vicente, Gonzalo   +5 more
core   +2 more sources

Modeling the Physical Characteristics of Ultrasound Pretreated Dialium guineense Whole Fruits Using Neural Network Pattern Recognition Model

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The study of Physical characteristics of agricultural materials is necessary for the design of processes and machines for food production. Length, width, thickness, sphericity, unit mass, and aspect ratio were the physical characteristics of ultrasound pretreated Dialium guineense whole fruits subjected to Neural network modeling.
Mfrekemfon Akpan, Uduak George, Okon Esua   +2 more
wiley   +1 more source

Optimization of microwave-assisted polyphenol extraction and antioxidant activity from papaya peel using response surface methodology and artificial neural network

Applied Food Research
The objective of the present study is to determine the optimal conditions of microwave-assisted extraction (MAE) such as microwave power (MWP), irradiation time (I-time), ethanol concentration (EtOH%), and solvent-to-solid ratio (S/S) for maximizing ...
Md. Waziur Rahman Chy, Tanvir Ahmed, Junaid Iftekhar, Md. Zohurul Islam, Md. Rahmatuzzaman Rana   +4 more
doaj   +1 more source

Rapid Estimation of Tocopherol Content in Linseed and Sunflower Oils-Reactivity and Assay

Molecules, 2015
The reactivity of tocopherols with 2,2-diphenyl-1-picrylhydrazyl (DPPH) was studied in model systems in order to establish a method for quantifying vitamin E in plant oils. The method was optimized with respect to solvent composition of the assay medium,
Tjaša Prevc, Alenka Levart, Irena Kralj Cigić, Janez Salobir, Nataša Poklar Ulrih, Blaž Cigić   +5 more
doaj   +1 more source

Soluble and insoluble-bound phenolics and antioxidant activity of various industrial plant wastes [PDF]

, 2019
The potential of selected industrial food wastes from juice and nut production including apple peel, apple pomace, pomegranate peel, pomegranate seed, chestnut shell, and black carrot pomace as resources for natural antioxidants was investigated. Soluble
Gulsunoglu, Zehra, Karbancioglu-Guler, Funda, Kilic-Akyilmaz, Meral, Raes, Katleen   +3 more
core   +2 more sources