Results 211 to 220 of about 127,218 (302)

Identification of diagnostic biomarkers for neonatal necrotizing enterocolitis via machine learning screening and single‐cell virtual gene knockout validation

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Integrated machine learning screening of five gene expression omnibus datasets and 113 algorithm combinations identified three candidate diagnostic biomarkers for neonatal necrotizing enterocolitis: SLC26A3 (downregulated), CCL20, and CXCL5 (both upregulated). Single‐cell RNA sequencing localized CCL20 upregulation predominantly to macrophages.
Xue Liu   +5 more
wiley   +1 more source

Inflammatory Neovascularization and Vascular Remodeling Associated With Carotid Plaque Destabilization

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
A subset of endothelial cells in the AC region promoted neovascularization, while the PA region exhibited an increase in osteogenic VSMCs, contributing to vascular remodeling. Fibroblast‐mediated inflammatory regulation was predominantly enriched in the PA region, whereas the AC region harbored more macrophage subsets involved in lipid metabolism and ...
Xuejiao Dai   +7 more
wiley   +1 more source

DRAM1‐defined autophagy‐JAK‐STAT‐Tregs axis drives immunosuppression and predicts immunotherapy response in pan‐cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Tumour‐intrinsic DRAM1, induced by DNA damage and IFN‐γ, activates an autophagy/JAK‐STAT axis that recruits Tregs, causing CD8+ T cell exhaustion and establishing a self‐sustaining, immunotherapy‐resistant “cold” tumour microenvironment. Abstract Background DNA damage‐regulated autophagy modulator 1 (DRAM1) is a lysosomal protein involved in autophagy ...
Jinchun Wu   +7 more
wiley   +1 more source

Effect of abdominoplasty with transverse plication on rectus diastasis. [PDF]

open access: yesJPRAS Open
Descarrega J   +7 more
europepmc   +1 more source

Alterations of circulating innate lymphoid cells in recent‐onset type 1 diabetes

open access: yesClinical &Translational Immunology, Volume 15, Issue 6, 2026.
Circulating innate lymphoid cells (ILC) in patients with recent‐onset type 1 diabetes (T1D) show a chronic activation and a primed phenotype, with overexpression of HLA Class II (ILC1 and ILCP) and dysregulation of costimulatory and migratory mRNA transcripts. Glucose and cytokines (IL‐1β) mediate circulating ILC activation and HLA Class II expression.
Ariadna Roig   +5 more
wiley   +1 more source

Sporadic Appetites: Unearthing the Fungal Diets of Two Mycophagous Mammals Across an Australian Climate Gradient

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
This study investigated the fungal dietary preferences of boodies and woylies across Mediterranean, semi‐arid and arid regions of Australia using DNA metabarcoding of scat samples, providing a comprehensive molecular characterisation of mycophagous feeding patterns for these species across broad climate gradients.
Rebecca J. Quah   +4 more
wiley   +1 more source

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

open access: yesGlia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma   +6 more
wiley   +1 more source

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