Results 131 to 140 of about 261,262 (302)
International Journal of Bio-Resource and Stress Management, 2018 Sustaining the healthy function and structure of natural ecosystems is a challenge, mainly due to the negative impacts of anthropogenic activities and climate change.
Valasia Iakovoglou, George N. Zaimes
doaj
Reconsidering hyogen education in Japan : drama for the whole person in the twenty-first century [PDF]
Hyogen (expression) education, which I received at elementary school and later university, has been one of major drama activities in the Japanese field of drama in schools.
Hida, Norifumi
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Constructivist inquiry and learning in drama
, 2007 Constructivism is an interpretive approach that emphasises the 'meaning making activity of the individual mind'. It is of particular relevance to drama education because learning in drama is based in process.
Wright, David
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Coming of age : dialogues about "Dramawise" and the elements of drama
, 2008 This article analyses and reflects on the impact of the work of Haseman and O'Toole and their book "Dramawise" now published 21 years ago. Drawing on interviews with them and other leading drama educators, the idea of their being certain core 'elements ...
Susan Davis (8992994), Davis, Susan.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
, 2013 This paper reports emergent findings from a reflective practitioner study on the aesthetics of process drama for teaching and learning additional languages (AL/process drama). In particular, in this paper I focus on the construct of 'engagement'. Firstly,
Piazzoli, Erika
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source