Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Effect of gynecological and breast cancer education using a creative drama method on midwifery students' awareness: a randomized controlled trial. [PDF]
BMC NursSayar SE, Barbak ZD.
europepmc +1 more source
An investigation into the space where drama education and dramatherapy meet. What does this mean in conceptual and practical terms for practitioner and participant? [PDF]
The aim of this research is to explore the space between drama education and dramatherapy as practised in the UK and find a way of describing it. I begin by looking at five areas relevant to both professions: theatre and anthropology, theatre and ...
Holmwood, Clive
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Role-playing interventions in adult psychotherapy: a systematic review of clinical applications, reported outcomes, and future directions. [PDF]
Front PsycholMazzucato M, Savastano M, Iudici A.
europepmc +1 more source
, 2002 The horrific events of the 11th of September 2001 are deeply etched in cultural memory through the images captured by numerous video cameras in New York City on that day.
Morelos, Ronaldo
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Effects of a combined physical activity and educational drama intervention on core symptoms and physical fitness in children with ASD. [PDF]
Sci RepMa B, Du X.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Reconfiguring institutional authority through Mood: a cross-cultural systemic functional analysis of Egyptian and American medical drama. [PDF]
Philos Ethics Humanit MedAli Hassan AM, Younis N.
europepmc +1 more source