Results 81 to 90 of about 261,262 (302)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Factors That Influence the Teachers’ Involvement in Outdoor, Nature-Based Educational Activities and Environmental Education Programs

open access: yesJournal of Zoological and Botanical Gardens
It is widely recognized that outdoor and nature-based educational activities can significantly enhance pupils’ learning, increase environmental awareness and improve pupils’ well-being.
Anastasia Chrysomalidou   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Dramaturgical Design Based on The Legend of Dideng Puti Dayang Ayu from Rantau Pandan

open access: yesMudra: Jurnal Seni Budaya
Dideng is an oral art from Rantau Pandan Village whose existence is of concern due to the lack of regeneration. In fact, Dideng art has theatrical, musical and gestural power.
Ikhsan Satria Irianto   +3 more
doaj   +1 more source

Sinonasal oncocytic Schneiderian papilloma limited to the inferior turbinate: a rare case [PDF]

open access: yesFolia Medica
Sinonasal oncocytic papilloma is a rare benign epithelial tumor arising from the Schneiderian mucosa, accounting for 3%-5% of all sinonasal papillomas. We present a case of a 67-year-old man with a history of non-Hodgkin lymphoma who presented with a one-
Constantinos Papadopoulos   +3 more
doaj   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Mu?ziğin Yaratıcı Drama Atölyelerindeki Rolu? ve Planlama Aşamalarında Etkin Kullanımı

open access: yes
Bu çalışma, mu?ziğin yaratıcı drama atölyelerindeki rolu?nu?; ısınma, canlandırma ve değerlendirme aşamalarında etkinliğini ve kullanım önerilerini belirlemeyi amaçlamaktadır. Çalışmada doku?man inceleme yöntemi kullanılmıştır.
Yapalı, Yunus
core   +1 more source

Teaching and learning through drama: stages of engagement in the dramatic presentation of experience [PDF]

open access: yes, 1993
This study looks at the nature of the children's engagement in the dramatic activities. It identifies seven stages of engagement in the dramatic presentation of experience. These stages have a conceptual as well as an empirical basis. In order to provide
Tsarouhi, Kalliope
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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