Results 111 to 120 of about 673,162 (334)
El Peldaño, 2017 Es la madrugada del 9 de octubre de 1841, noche tan clara que se confunde con la mañana. Los personajes son Juan Galo Lavalle, llagado y febril, y su Damasita Boedo, que inicia vestida de soldado queriendo aprender a tirar, a empuñar la tercerola, para ...
Roxana Aramburú
doaj
Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Las distintas funciones universitarias como procesos relacionales
El Peldaño, 2017 El objetivo de este trabajo es exponer la manera en la cual se fueron relacionando, a lo largo de los años, las diferentes funciones que desarrollo en la Facultad de Arte de la Universidad Nacional del Centro: la docencia, la investigación y la extensión.
Prof. Mag. Martín Rosso
doaj
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Tato Pavlovsky y Elvira Onetto
El Peldaño, 2015 En Octubre de 2014 se realizaron en la Facultad de Arte las primeras Jornadas de Dirección en Artes escénicas1. En este marco se presentó la obra Asuntos Pendientes de Tato Pavlovsky; con dirección de Elvira Onetto y las actuaciones de Susy Evans ...
Mg. Paula Fernandez, Mg. Gabriela Gonzalez, Lic. Jerónimo Ruiz y Lic.Agustina Fitipaldi
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh +3 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source