Results 51 to 60 of about 2,836,246 (305)

Energy Models for Graph Clustering

Journal of Graph Algorithms and Applications, 2007
The cluster structure of many real-world graphs is of great interest, as the clusters may correspond e.g. to communities in social networks or to cohesive modules in software systems.
Andreas Noack
doaj   +1 more source

Mathematical modeling of the technological process of twisting a waveguide

Космические аппараты и технологии, 2023
Twisted waveguides are part of waveguide paths of antenna- feeder devices of spacecraft. They have high requirements for accuracy and reliability. They are made of profiled rectangular pipes.
V. V. Timofeev, I. V. Trifanov, E. V. Patraev   +2 more
doaj   +1 more source

Sync-and-Burst: Force-Directed Graph Drawing with Uniform Force Magnitudes

CoRR, 2015
We introduce a force-directed algorithm, called Sync-and-Burst, which falls into the category of classical force-directed graph drawing algorithms. A distinct feature in Sync-and-Burst is the use of simplified forces of attraction and repulsion whose magnitude does not depend on the distance between vertices.
Farshad Ghassemi Toosi, Nikola S. Nikolov   +1 more
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Quntitative structure activity relationship (QSAR) of UV-visible spectrum of some different chalkons [PDF]

شیمی کاربردی روز, 2013
  The UV-visible spectrum of some different chalkons with both electron with-drawing and electron-donating groups have been investigated. The results showed that electron with-drawing groups cause Blue-Shift and electron-donating groups cause Red-Shift.
Salman Rahmani, Ali Amoozadeh
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Determining the Drawing Force in a Wire Drawing Process Considering an Arbitrary Hardening Law

Processes, 2022
The present paper considers the wire drawing process through a conical die and provides an approximate solution for the drawing force, assuming an arbitrary hardening law. The solution is based on the upper bound theorem. However, this theorem does not apply to the stationary flow of strain-hardening materials.
Alexandrov, Sergei, Hwang, Yeong-Maw, Tsui, Hiu   +2 more
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source