Results 111 to 120 of about 837,527 (297)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Effect of Forming Parameters on the Fracture Behaviour of AISI 430 Steel in Draw-Bend Fracture Test

Advances in Mechanical and Materials Engineering
The draw-bend fracture (DBF) test was used to simulate the different forming conditions of AISI 430 steel strips with thickness of 0.8 mm. The tests were performed for varying test parameters such tool radius, drawing speed and strip orientation.
Valmir Dias Luiz, Almir Silva Neto, Wilian da Silva Labiapari, Paulo César de Matos Rodrigues   +3 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

基于图标菜单的常用机构运动简图的二次开发

Jixie chuandong, 2004
A software package is developed to make diagram drawing of mechanisms under the Auto CAD 2000. The visualized sign, icon menu, pull-down menu are used to help the designer to make the interactive drawing of mechanism diagrams at high speed.
吕守祥, 贺炜, 刘言松, 吴春英
doaj  

Influence of a cold deformation process by drawing on the electrical properties of copper wires

REM: International Engineering Journal
This article presents a study of the drawing, deformation, hardening and heat treatment of copper wire, in order to investigate the influence of combinations of operating variables (annealing factor, oil emulsion temperature and machine speed) during the
Rafael da Silva Bernardo, Marcolino Fernandes Neto   +1 more
doaj   +1 more source

Preparation of High Modulus Poly(Ethylene Terephthalate): Influence of Molecular Weight, Extrusion, and Drawing Parameters

International Journal of Polymer Science, 2017
Poly(ethylene terephthalate) (PET) which is one of the most commercially important polymers, has for many years been an interesting candidate for the production of high performance fibres and tapes. In current study, we focus on investigating the effects
Jian Min Zhang, Qingsong Hua, Christopher T. Reynolds, Yuling Zhao, Zuoqiang Dai, Emiliano Bilotti, Jie Tang, Ton Peijs   +7 more
doaj   +1 more source

The Influence of Drawing Speed on Steel Wire Surface Quality

Publikationer från Örebro universitet, 2022
Wire drawing is a cold-working process in which a wire is pulled through a drawing die, resulting in plastic deformation of the material and wire diameter reduction. One important parameter in the wire drawing process is the drawing speed. An increased drawing speed can improve productivity, which is desired for the company Suzuki Garphyttan AB due to ...
Viklund, Felicia, Lundin Bornström, Amanda   +1 more
openaire   +1 more source

Method for horizontally growing ribbon crystal [PDF]

A high speed method for forming ribbon crystal of desired width and thickness is characterized by drawing out the ribbon through a space whose distance is 5.7 times that of the thickness of the grown ribbon.
Kudo, B.
core   +1 more source