Results 91 to 100 of about 837,527 (297)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The paper analyzes force parameters in the process of multistage drawing of steel wires in conventional and hydrodynamic dies. The drawing process of the wire rod with a diameter of 5.5 mm for wires with a diameter of 1.70 mm was performed in 12 drafts ...
Suliga M.
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Projekt for manufacturing of gears for Company Stab spol. s r. o. [PDF]
Diplomová práca opisuje projekt na založenie novej divízie pre firmu ktorá sa zaoberá generálnymi opravami strojov. V prvej časti práce je rozoberaná teoretická časť o výrobnom procese ozubenia a ekonomická časť tejto práce. Hlávne časti práce sú analýza
Štefan Staník
core
A conceptual design tool: Sketch and fuzzy logic based system [PDF]
A real time sketch and fuzzy logic based prototype system for conceptual design has been developed. This system comprises four phases. In the first one, the system accepts the input of on-line free-hand sketches, and segments them into meaningful parts ...
Jordanov, IN, Qin, SF, Wright, DK
core
Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz +25 more
wiley +1 more source
In this study, effect of drawing speed and flange temperature on formability of cylindrical cup warm deep drawing of AZ31 magnesium alloy sheet is clarified experimentally. For the purpose, a new locally heating and cooling deep drawing apparatus is designed and developed. Magnesium alloy used is AZ31 sheet with 0.5mm thickness.
Ken-ichi MANABE, Osamu SHIMOMURA
openaire +2 more sources
RC rate generator for slow speed measurement Patent [PDF]
Device utilizing RC rate generators for continuous slow speed ...
Loyd, C., Mccampbell, W. M.
core +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source

