Results 221 to 230 of about 163,636 (279)

Dried Blood Spots in Doping Analysis

Bioanalysis, 2021
A series of dried blood spot (DBS) detection methods for doping agents have been developed in the last two decades. The DBS technique minimizes invasiveness and reduces storage and shipping costs. Recently, the World Anti-Doping Agency announced the use of DBS for the 2022 Beijing Winter Olympic Games and Paralympic Games owing to the advantages of the
Yuling Yuan, Youxuan Xu, Jianghai Lu
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Stabilized dried blood spot collection

Analytical Biochemistry, 2016
During the collection phase of the dried blood spot method, practitioners need to ensure that there is no smearing of the blood sample on the filter paper or else readings from it will be invalid. This can be difficult to accomplish in the field if there is relative motion between the site of blood discharge on the finger and the filter paper.
Darren, McMorran, Dwayne Chung Kim, Chung, Monika, Toth, Oi Wah, Liew, Murat, Muradoglu, Tuck Wah, Ng   +5 more
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Measuring thiamine status in dried blood spots

Clinica Chimica Acta, 2020
A reliable and robust method with minimum sample collection requirement for thiamine assay is needed in clinical and research settings.A simple and robust assay for three vitamers (thiamine, Th; thiamine monophosphate, TMP; and thiamine diphosphate, TDP) using a 6.35-mm dried blood spot (DBS) disc was developed, validated and applied.We were able to ...
Yichao Huang, Robert A. Gibson, Timothy J. Green   +2 more
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Glutathione peroxidase in dried blood spots

Experientia, 1978
A new procedure utilizing dried blood spots was developed for detecting glutathione peroxidase deficiency. Samples from a known patient with a partial defect and from rats with an induced deficiency were distinguished from respective control groups by their longer defluorescence endpoints.
S, Kelly, L, Schedlbauer
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C-peptide in dried blood spots

Scandinavian Journal of Clinical and Laboratory Investigation, 2010
The aim was to evaluate if the Dried Blood Spot (DBS)-technique can be used to analyse C-peptide. S-C-peptide and paired whole blood clotted on filters, dried, punched out and eluted were sampled from 198 healthy subjects. Six subjects with S-C-peptide values outside the reference range were excluded.
Jesper, Johansson, Charlotte, Becker, Nils-Göran, Persson, Malin, Fex, Carina, Törn   +4 more
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Quantification of insulin in dried blood spots

Journal of Laboratory and Clinical Medicine, 1998
A method has been developed in which the concentrations of insulin in dried blood spots on filter paper can be estimated. The technique involves elution of blood from the paper, evaporation, and rehydration in assay buffer. The resuspended samples are then assayed by radioimmunoassay.
B, Dowlati, P A, Dunhardt, M M, Smith, S, Shaheb, C A, Stuart   +4 more
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Radioimmunoassay of Thyroxine in Dried Blood Spots

Journal of Paediatrics and Child Health, 1978
Sadler, W. A., Lynskey, Clare P., and Legge, M. (1978). Aust. Paediatr. J., 14, 154–182. Radioimmunoassay of thyroxine in dried blood spots. A rapid precise radioimmunoassay for thyroxine (T4) in dried blood spots on filter paper has been developed, and appears entirely suitable for use as a mass screening procedure for the early diagnosis of neonatal ...
W A, Sadler, C P, Lynskey, M, Legge
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Discovery stage pharmacokinetics using dried blood spots

Journal of Chromatography B, 2004
Early in the discovery stage, the measurement of drug candidates in biological fluids as a function time provides important information used in decision making for lead optimization. The detection methodology primarily used is liquid chromatography coupled to triple quadrupole mass spectrometry (LC-MS).
Patrick, Beaudette, Kevin P, Bateman
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What Is Next For Dried Blood Spots?

Bioanalysis, 2012
In the last several years, dried blood spot (DBS) sampling has re-emerged and attracted a great interest in the pharmaceutical industry as a microsampling technology for drug discovery and development studies. Although significant progress has been made to understand strengths and weaknesses of the technique, many organizations are still at the ...
Qin C, Ji, Guowen, Liu, Celia J, D'Arienzo, Timothy V, Olah, Mark E, Arnold   +4 more
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Dried blood spots

Current Pharmaceutical Design, 2011
Tuberculosis (TB) is a high-burden infectious disease, especially in low and middle-income countries. The efforts to eliminate this disease are challenged by the emergence of multidrug resistance and TB-HIV coinfection. The cumulative knowledge on pharmacokinetics/pharmacodynamics of antituberculosis agents has recently encouraged therapeutic drug ...
Vu, D.H., Alffenaar, J.W., Edelbroek, P.M., Brouwers, J.R., Uges, D.R.   +4 more
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