Results 51 to 60 of about 2,829,518 (302)

Barriers to expeditious dried blood spot testing and potential solutions.

open access: yes, 2015
Barriers to expeditious dried blood spot testing and potential solutions.
Jennifer A. Downs (338102)   +4 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA. [PDF]

open access: yesPLoS ONE, 2016
Stored neonatal dried blood spot (DBS) samples from neonatal screening programmes are a valuable diagnostic and research resource. Combined with information from national health registries they can be used in population-based studies of genetic diseases.
Jesper Buchhave Poulsen   +19 more
doaj   +1 more source

Detection of Cotinine in Newborn Dried Blood Spots [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2007
AbstractMaternal smoking while pregnant is a plausible risk factor for childhood cancers because many seem to initiate in utero and tobacco-specific carcinogens cross the placenta. Social desirability bias may affect maternal report of smoking in case-control studies and could explain inconsistently observed associations with offspring cancer ...
Logan G, Spector   +4 more
openaire   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Analysis of Acrylamide and Glycidamide in Dried Blood Spot of Smokers Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

open access: yesDrug Design, Development and Therapy, 2022
Yahdiana Harahap,1,2 Afaf Amma Lahilla,1 Anastasia Sharon Jautan,1 Amiral Hafidz,1 Sunarsih Sunarsih3 1Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; 2Faculty of Military Pharmacy, Republic of Indonesia Defense University, Bogor, Indonesia;
Harahap Y   +4 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Comparison of the developed dried matrix spot methods with conventional sampling procedures.

open access: yes, 2015
vP plasma sample from venous blood, vDPS dried plasma spot from venous blood, vDBSP dried blood spot with plasma folate determination from venous blood, fDBSP dried blood spot with plasma folate determination from finger blood, vWB whole blood sample ...
Markus Kopp (831010)   +1 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

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