Results 61 to 70 of about 2,631,684 (301)

Stability of Proteins in Dried Blood Spot Biobanks

Molecular & Cellular Proteomics, 2017
An important motivation for the construction of biobanks is to discover biomarkers that identify diseases at early, potentially curable stages. This will require biobanks from large numbers of individuals, preferably sampled repeatedly, where the samples are collected and stored under conditions that preserve potential biomarkers.
Björkesten J, Enroth S, Shen Q, Wik L, Hougaard DM, Cohen AS, Sörensen L, Giedraitis V, Ingelsson M, Larsson A, Kamali-Moghaddam M, Landegren U   +11 more
openaire   +5 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

A Novel Dried Blood Spot Detection Strategy for Characterizing Cardiovascular Diseases

Frontiers in Cardiovascular Medicine, 2020
Cardiovascular diseases (CVDs) are the leading cause of death in China. Conventional diagnostic methods are dependent on advanced instruments, which are expensive, inaccessible, and inconvenient in underdeveloped areas. To build a novel dried blood spot (
Linsheng Liu, Xurui Jin, Yangfeng Wu, Mei Yang, Tao Xu, Tao Xu, Xianglian Li, Jianhong Ren, Lijing L. Yan   +8 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Dried Blood Spot Sampling for Monitoring Children With Immune-Mediated Glomerulopathies and After Kidney Transplantation

Kidney International Reports
Introduction: Monitoring kidney function and immunosuppressant levels in children post–kidney transplantation or those with glomerulopathies is challenging due to frequent venipunctures and clinic visits.
Lena Brunkhorst, Michael Terhardt, Björn Bulitta, Miriam Gutting, Nils Janzen, Dieter Haffner, Nele Kanzelmeyer   +6 more
doaj   +1 more source

A pilot screening of high-risk Gaucher disease children using dried blood spot methods in Shandong province of China

Orphanet Journal of Rare Diseases, 2018
Background The study aim was to verify the feasibility of a diagnostic algorithm with the evaluation of beta glucocerebrosidase (GBA) activity on dried blood spots (DBS) in screening high-risk Gaucher disease (GD) children in China, and to investigate ...
Ke Lei, Yanxia Zhao, Lirong Sun, Hui Liang, Ronghua Luo, Xiaojing Sun, Yanling Tao, Lijun Chen, Lingling Zhang, Aimin Li, Fu Li, Hongfang Ding   +11 more
doaj   +1 more source

Sample selection for dried blood spot (DBS) analysis.

, 2016
Sample selection for dried blood spot (DBS) analysis.
Amy S. Nunn (3164523), Alexi Almonte (3164520), Peter Anderson (202780), Rupa Patel (1341582), Philip A. Chan (343985), Kenneth H. Mayer (116219), Teri Liegler (358933), Madeline C. Montgomery (3164529), Catherine E. Oldenburg (433905), Leandro Mena (3164526)   +9 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Monitoring of SARS-CoV-2 antibodies using dried blood spot for at-home collection

Scientific Reports, 2022
The utilization of vaccines to fight the spread of SARS-CoV-2 has led to a growing need for expansive serological testing. To address this, an EUA approved immunoassay for detection of antibodies to SARS-CoV-2 in venous serum samples was investigated for
Peyton K. Miesse, Bradley B. Collier, Russell P. Grant   +2 more
doaj   +1 more source

Dried blood spots: An evaluation of utility in the field

Journal of Infection and Public Health, 2018
Use of dried blood spots (DBS) offers advantages over serum samples in studies conducted in resource-poor settings. The aim of this study was to compare the number of adequate spots collected across different demographic groups.Five DBS were collected from 3316 individuals aged 0-49 years in Tianjin, China for a measles antibody study; DBS were rated ...
Xu Su, Bradley F. Carlson, Xiexiu Wang, Xiaoyan Li, Ying Zhang, JoLynn P. Montgomery, Yaxing Ding, Abram L. Wagner, Brenda Gillespie, Matthew L. Boulton   +9 more
openaire   +3 more sources