Results 81 to 90 of about 163,636 (279)

Analysis of Acrylamide and Glycidamide in Dried Blood Spot of Smokers Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

Drug Design, Development and Therapy, 2022
Yahdiana Harahap,1,2 Afaf Amma Lahilla,1 Anastasia Sharon Jautan,1 Amiral Hafidz,1 Sunarsih Sunarsih3 1Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; 2Faculty of Military Pharmacy, Republic of Indonesia Defense University, Bogor, Indonesia;
Harahap Y, Lahilla AA, Jautan AS, Hafidz A, Sunarsih S   +4 more
doaj  

Therapeutic drug monitoring of tacrolimus and mycophenolic acid in outpatient renal transplant recipients using a volumetric dried blood spot sampling device

British Journal of Clinical Pharmacology, 2018
Tacrolimus and mycophenolic acid dosing after renal transplantation is individualized through therapeutic drug monitoring (TDM). Home‐based dried blood spot (DBS) sampling has the potential to replace conventional TDM sampling at the clinic.
Tom C. Zwart, Sumit R M Gokoel, P. V. D. van der Boog, J. D. de Fijter, D. Kweekel, J. Swen, H. Guchelaar, D. Moes   +7 more
semanticscholar   +1 more source

Dried Blood Spots May Improve Detection of Blood Doping [PDF]

Clinical Chemistry, 2019
In 2019, investigations have found at least 40 blood bags, 5 cross-country skiers, 5 cyclists, and 1 physician involved in a highly sophisticated blood doping scandal (1). The findings highlight the need for improved detection of blood doping practices.
openaire   +2 more sources

Retinol-Binding Protein Stability in Dried Blood Spots [PDF]

Clinical Chemistry, 2007
Abstract Background: Retinol-binding protein (RBP) is accepted as a surrogate biochemical marker for retinol to determine vitamin A (VA) status. A recently developed enzyme immunoassay for RBP uses serum or whole blood stored as dried blood spots (DBS). However, the stability of RBP in DBS has not been examined.
Masako, Fujita, Eleanor, Brindle, Jane, Shofer, Philip, Ndemwa, Yeri, Kombe, Bettina, Shell-Duncan, Kathleen A, O'Connor   +6 more
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A Novel Dried Blood Spot Detection Strategy for Characterizing Cardiovascular Diseases

Frontiers in Cardiovascular Medicine, 2020
Cardiovascular diseases (CVDs) are the leading cause of death in China. Conventional diagnostic methods are dependent on advanced instruments, which are expensive, inaccessible, and inconvenient in underdeveloped areas. To build a novel dried blood spot (
Linsheng Liu, Xurui Jin, Yangfeng Wu, Mei Yang, Tao Xu, Tao Xu, Xianglian Li, Jianhong Ren, Lijing L. Yan   +8 more
doaj   +1 more source

Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients [PDF]

, 2016
Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies investigating the disposition of PZQ enantiomers (R- and S-PZQ) and ...
Duthaler, Urs, Huwyler, Jörg, Keiser, Jennifer, Kovac, Jana, Meister, Isabel, Odermatt, Peter, Sayasone, Somphou, Vanobberghen, Fiona   +7 more
core   +2 more sources

Diagnostic accuracy of detection and quantification of HBV-DNA and HCV-RNA using dried blood spot (DBS) samples – a systematic review and meta-analysis

BMC Infectious Diseases, 2017
BackgroundThe detection and quantification of hepatitis B (HBV) DNA and hepatitis C (HCV) RNA in whole blood collected on dried blood spots (DBS) may facilitate access to diagnosis and treatment of HBV and HCV infection in resource-poor settings.
B. Lange, T. Roberts, J. Cohn, Jamie Greenman, J. Camp, A. Ishizaki, Luke Messac, E. Tuaillon, P. Van de Perre, C. Pichler, Claudia M. Denkinger, P. Easterbrook   +11 more
semanticscholar   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Detection of Cotinine in Newborn Dried Blood Spots [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2007
AbstractMaternal smoking while pregnant is a plausible risk factor for childhood cancers because many seem to initiate in utero and tobacco-specific carcinogens cross the placenta. Social desirability bias may affect maternal report of smoking in case-control studies and could explain inconsistently observed associations with offspring cancer ...
Logan G, Spector, Stephen S, Hecht, Simona, Ognjanovic, Steven G, Carmella, Julie A, Ross   +4 more
openaire   +2 more sources