Results 61 to 70 of about 5,304,999 (294)

HCV microelimination in harm reduction centres has benefits beyond HCV cure but is hampered by high reinfection rates

JHEP Reports, 2022
Background & Aims: Significant scale-up of treatment among people who inject drugs (PWID) is crucial to achieve WHO HCV elimination targets. We explored the impact of on-site HCV diagnosis and treatment on PWID in an externalised hepatology clinic at
Sabela Lens, Anna Miralpeix, Mont Gálvez, Elisa Martró, Noemi González, Sergio Rodríguez-Tajes, Zoe Mariño, Verónica Saludes, Juliana Reyes-Urueña, Xavier Majó, Joan Colom, Xavier Forns   +11 more
doaj   +1 more source

Flow diagram of steps required for rural dried blood spot HIV viral load testing and median times to completion at baseline.

, 2015
Flow diagram of steps required for rural dried blood spot HIV viral load testing and median times to completion at baseline.
Jennifer A. Downs (338102), Anna Mwale (821182), Luke R. Smart (523462), Kedar S. Mate (237835), Sabina Manumbu (821181)   +4 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Integrating enzyme assay and molecular genetic testing for early diagnosis of infantile-onset Pompe disease: A case report

Molecular Genetics and Metabolism Reports
Background: Infantile-onset Pompe disease is a severe lysosomal storage disorder caused by biallelic pathogenic variants in GAA, leading to deficient acid α-glucosidase activity.
Anuradha Sharma, Minakshi Vashist, Rohit Kaushik, Gulshan Rohilla, Sonia Narwal   +4 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Perspectıves of mothers and expectant mothers on newborn screening tests: a qualitative study

Scientific Reports
This study aimed to examine in depth the thoughts of pregnant women and mothers in the first six months postpartum regarding newborn screening tests using qualitative research method.
Hilal Aksoy, Elif Hilal Ünverdi, Elif Buse Şahin, Ayşe Esra Tapçı, İzzet Fidancı, Duygu Ayhan Başer   +5 more
doaj   +1 more source

Early infant diagnosis: A new tool of HIV diagnosis in children

Indian Journal of Community Medicine, 2011
Background: Standard assay has limited utility in diagnosing HIV reactivity among infants till the age of 18 months by which time, many HIV-infected infants expire.
Kamlesh Kumar Jain, Raj Kumar Mahajan, Manoj Shevkani, Pradeep Kumar   +3 more
doaj   +1 more source

Sample selection for dried blood spot (DBS) analysis.

, 2016
Sample selection for dried blood spot (DBS) analysis.
Amy S. Nunn (3164523), Alexi Almonte (3164520), Peter Anderson (202780), Rupa Patel (1341582), Philip A. Chan (343985), Kenneth H. Mayer (116219), Teri Liegler (358933), Madeline C. Montgomery (3164529), Catherine E. Oldenburg (433905), Leandro Mena (3164526)   +9 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source