Results 41 to 50 of about 5,304,999 (294)
Fabry Cardiomyopathy: Current Practice and Future Directions
Cells, 2021 Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations in the galactosidase A (GLA) gene that result in deficient galactosidase A enzyme and subsequent accumulation of glycosphingolipids throughout the body.
Jeffrey Yim +3 more
doaj +1 more source
Southern African Journal of Infectious Diseases, 2018 Objectives:Rapid human immunodeficiency virus (HIV) antibody tests, routinely used for diagnosis in adults and older children in resource-limited settings (RLS), do not detect early HIV infections prior to seroconversion or when antibody levels are still
Wentzel Dowling +9 more
doaj +1 more source
Dried blood spots are a valid alternative to venipuncture for COVID-19 antibody testing
Journal of Immunological Methods, 2023 Serologic analysis is an important tool towards assessing the humoral response to COVID-19 infection and vaccination. Numerous serologic tests and platforms are currently available to support this line of testing. Two broad antibody testing categories are point-of-care lateral flow immunoassays and semi-quantitative immunoassays performed in clinical ...
Sims, Matthew D. +10 more
openaire +2 more sources
Precision of Serologic Testing from Dried Blood Spots Using a Multiplex Bead Assay [PDF]
The American Journal of Tropical Medicine and Hygiene, 2021 ABSTRACT. Multiplex bead assays (MBAs) for serologic testing have become more prevalent in public health surveys, but few studies have assessed their test performance. As part of a trachoma study conducted in a rural part of Ethiopia in 2016, dried blood spots (DBS) were collected from a random sample of 393 children aged 0 to 9 years, with at least ...
Gwyn, Sarah +12 more
openaire +4 more sources
Barriers to expeditious dried blood spot testing and potential solutions.
, 2015 Barriers to expeditious dried blood spot testing and potential solutions.
Jennifer A. Downs (338102) +4 more
core +1 more source
International Journal of Neonatal Screening, 2023 In this retrospective study, we aimed to evaluate the performance of dried-blood-spot (DBS) testing as a diagnostic method for the congenital cytomegalovirus (cCMV).
Ana Del Valle Penella +3 more
doaj +1 more source
Next-Generation Molecular Testing of Newborn Dried Blood Spots for Cystic Fibrosis [PDF]
The Journal of Molecular Diagnostics, 2016 Newborn screening for cystic fibrosis enables early detection and management of this debilitating genetic disease. Implementing comprehensive CFTR analysis using Sanger sequencing as a component of confirmatory testing of all screen-positive newborns has remained impractical due to relatively lengthy turnaround times and high cost.
Lefterova, Martina I. +10 more
openaire +2 more sources
A rapid method for DNA Isolation from blood, dried blood spots and rapid diagnosis test
Journal of Vector Borne Diseases, 2023 Background & objectives: Malaria is a parasitic disease spread by Plasmodium parasite. Microscopy, lateral flow devices such as the Rapid Diagnostic Test (RDT), molecular methods such as Polymerase Chain Reaction (PCR), isothermal methods ...
Supriya Sharma +4 more
openaire +3 more sources
Postal methods for monitoring HbA1c in diabetes mellitus: a protocol for systematic review
BJGP Open, 2022 Background: Worldwide there are an estimated 463 million people with diabetes. In the UK people with diabetes are offered annual review, which includes monitoring of haemoglobin A1c (HbA1c).
Jack Colley +4 more
doaj +1 more source
Newborn Genetic Screening—Still a Role for Sanger Sequencing in the Era of NGS
International Journal of Neonatal Screening, 2023 In the Norwegian newborn screening (NBS) program, genetic testing has been implemented as a second or third tier method for the majority of NBS disorders, significantly increasing positive predictive value (PPV).
Silje Hogner +5 more
doaj +1 more source