Background: Dried bloodspots are easy to collect and to transport to assess various metabolites, such as amino acids. Dried bloodspots are routinely used for diagnosis and monitoring of some inherited metabolic diseases.
Julien Baruteau +10 more
doaj +1 more source
The quality and quantity of compounds affected by viral inactivation methods in dried blood spots
The aim is to evaluate the effect of viral inactivation methods on the quality and quantity of compounds in dried blood spots (DBS).
Wang Ming +5 more
doaj +1 more source
Non-adherence to cardiovascular pharmacotherapy in Iraq assessed using 8-items Morisky questionnaire and analysis of dried blood spot samples [PDF]
open access journalThe study evaluated the non-adherence to selected cardiovascular medications, atenolol, atorvastatin, bisoprolol, diltiazem, lisinopril, simvastatin and valsartan in Iraqi patients by applying a standardized Morisky questionnaire (8 ...
Alalaqi, Ahmed +3 more
core +1 more source
Dried Blood Spots May Improve Detection of Blood Doping [PDF]
In 2019, investigations have found at least 40 blood bags, 5 cross-country skiers, 5 cyclists, and 1 physician involved in a highly sophisticated blood doping scandal (1). The findings highlight the need for improved detection of blood doping practices.
openaire +2 more sources
Retinol-Binding Protein Stability in Dried Blood Spots [PDF]
Abstract Background: Retinol-binding protein (RBP) is accepted as a surrogate biochemical marker for retinol to determine vitamin A (VA) status. A recently developed enzyme immunoassay for RBP uses serum or whole blood stored as dried blood spots (DBS). However, the stability of RBP in DBS has not been examined.
Masako, Fujita +6 more
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Utilization of archived neonatal dried blood spots for genome-wide genotyping.
IntroductionHeel pricks are performed on newborns for diagnostic screenings of various pre-symptomatic metabolic and genetic diseases. Excess blood is spotted on Guthrie cards and archived by many states in biobanks for follow-up diagnoses and public ...
Pagna Sok +8 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Attitudes About the Use of Newborn Dried Blood Spots for Research: A Survey of Underrepresented Parents [PDF]
Objective To identify the relative importance of factors that impact parents’ attitudes toward use of their child’s dried newborn blood spots for research purposes.
Carroll, Aaron E. +3 more
core +1 more source
Detection of Cotinine in Newborn Dried Blood Spots [PDF]
AbstractMaternal smoking while pregnant is a plausible risk factor for childhood cancers because many seem to initiate in utero and tobacco-specific carcinogens cross the placenta. Social desirability bias may affect maternal report of smoking in case-control studies and could explain inconsistently observed associations with offspring cancer ...
Logan G, Spector +4 more
openaire +2 more sources

