Results 61 to 70 of about 638,433 (245)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Exploiting Evolution for an Adaptive Drift-Robust Classifier in Chemical Sensing [PDF]
, 2010 Gas chemical sensors are strongly affected by drift, i.e., changes in sensors' response with time, that may turn statistical models commonly used for classification completely useless after a period of time.
Stefano Di Carlo +12 more
core +1 more source
ICPBR-Working Group Risks posed by dusts: overview of the area and recommendations
Julius-Kühn-Archiv, 2012 Background: In 2008 the poisoning of about 12000 bee colonies was reported from Germany. These poisonings were caused by the drift of dust particles containing the insecticidal substance clothianidin following the seeding of maize seeds, inadequately ...
Forster, Rolf +7 more
doaj +1 more source
Nonlinear Seismic Response of Multistory Steel Frames with Self-Centering Tension-Only Braces
Applied Sciences, 2020 The self-centering tension-only brace (SC-TOB) is a new and innovative bracing system that provides both a flag-shaped recentering hysteresis and load mitigation to structures.
Pei Chi +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Other title: Hazard Mitigation Plan
, 2013 [Revised] October 14, 2013 Includes bibliographical and internet references.The purpose of the Kansas Hazard Mitigation Plan is to guide hazard mitigation to better protect the people and property of the State.
Kansas Hazard Mitigation Team.
core +1 more source
Stochastic Evolutionary Dynamics: Drift vs. Draft [PDF]
, 2004 In a small handful of papers in theoretical population genetics, John Gillespie argues that a new stochastic process he calls "genetic draft" is evolutionarily more significant than genetic drift. This case study of chance in evolution explores Gillespie'
Skipper, Robert
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Dust drift during sowing of maize - effects on honey bees
Julius-Kühn-Archiv, 2012 Background: Bee poisoning incidents in southern Germany in 2008 revealed drift of insecticidal dusts of treated maize seed during sowing on adjacent areas with flowering bee forage plants as a considerable route of exposure.
Georgiadis, Pablo-Th. +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source