Results 91 to 100 of about 5,147,496 (260)
Advanced Science, EarlyView.This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu +9 more
wiley +1 more source
Environment InternationalTaiwan’s mid-20th-century Blackfoot disease epidemic highlighted the public health implications of geogenic arsenic in groundwater and prompted extensive water-supply interventions.
Kai-Yun Li +5 more
doaj +1 more source
Kansas Drinking Water Annual Compliance Report
, 2014 This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water
core
Maximum Contaminant Level Recommendation Document on Radon-222
, 2009 Radon is a carcinogen known to occur in New Jersey drinking water supplies at often high levels, with resulting high health risks. The Institute reviewed health effects, analytical methods and New Jersey certified laboratory testing capabilities, and ...
core +1 more source
Advanced Science, EarlyView.Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang +12 more
wiley +1 more source
PURIFICATION OF DRINKING WATER [PDF]
The Journal of Nervous and Mental Disease, 1891 n ...
openaire +1 more source
Kansas Drinking Water Annual Compliance Report, 2011
, 2012 This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water
core
Advanced Science, EarlyView.Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao +5 more
wiley +1 more source
Kansas Drinking Water Annual Compliance Report
, 2018 This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water
core
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Advanced Science, EarlyView.Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source