Results 111 to 120 of about 5,147,496 (260)

Urine metabolomic characteristics of people exposed to hexavalent chromium in drinking water

Ecotoxicology and Environmental Safety
This study investigated the toxicological mechanisms of hexavalent chromium (Cr(VI)) exposure on human health by analyzing the urinary metabolomics of residents exposed to Cr(VI) through drinking water.
Tao Yanan, Hu Miaomiao, Xia Yunting, Peng Fangda, Xiong Chuanlong, Ding Chunguang   +5 more
doaj   +1 more source

OTHER TITLES: Annual Compliance Report. Public Water Supply: Annual Compliance Report for 2020. Kansas Drinking Water Annual Compliance Report

, 2020
This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas Department of Health and Environment, Bureau of Water, Public Water Supply Section
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EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Other title: Kansas Drinking Water Annual Compliance Report, 2000

, 2001
July 2001This report is a summary of Kansas water system's compliance with drinking water regulations for the calendar ...
Kansas. Department of Health and Environment, Bureau of Water
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Post-wildfire monitoring guidance for drinking water systems

, 2020
Title from PDF caption (viewed on November 20, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Organophosphate esters in reservoir water from a metropolitan city in the Guangdong-Hong Kong-Macao Greater Bay Area, China, and their ecological risk

Emerging Contaminants
Organophosphate esters (OPEs) are emerging flame retardants widely used in products such as furniture, electronic equipment, construction, and plastics. It has been demonstrated that OPEs are harmful to humans and aquatic organisms, thus posing a threat ...
Yi Huang, Yiming Ge, Chenglin Li, Linshen Xie, Xiujuan Qi, Pu Ye, Xixiang Guo, Chen Deng, Rong Hu, Jinling Wang, Yihong Liu, Bei Wang, Tingting Zhu, Shaoyou Lu   +13 more
doaj   +1 more source

Funded projects [PDF]

, 2018
Title from PDF caption (viewed on January 15, 2021)."These projects will enhance habitat for Coho, Chinook, Steelhead, Lamprey, Bull trout, and Cutthroat trout as well as water quality for the 877,000 people who rely on these streams and rivers for their

core  

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source