Results 101 to 110 of about 1,115,153 (282)

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Changes of Physicochemical Characteristics of Microplastics During Water Disinfection Processes: A Review

能源环境保护
Microplastic pollution in aquatic environments has drawn widespread attention. In addition to the toxicity and ecological risks, microplastics can act as carriers of various pollutants. In water disinfection processes, disinfectants can induce changes in
Shuo ZHANG, Xian ZHANG, Hang LIU, Chenhao TIAN, Miao WANG, Guoqi SHI, Chao LIU   +6 more
doaj   +1 more source

Survey of Microbial Quality of Drinking Water in Rural Areas of Saqqez, Iran [PDF]

Safety drinking water providing is one of the main purposes for community development and improvement. Having a healthy community is related to the safe drinking water. In this study, we surveyed the microbial quality of 116 villages under cover of the
دهقانی, محمدهادی, زارعی, احمد, فضل زاده دویل, مهدی, قادرپوری, منصور   +3 more
core  

Occurrence of transparent exopolymer particles (TEP) through drinking water treatment plants [PDF]

, 2011
Numerous membrane fouling studies have been conducted to predict and prevent membrane fouling. It was only recently that a new parameter, TEP, was introduced in this research.
Boon, Nico, Hennebel, Tom, Van Nevel, Sam, Verstraete, Willy   +3 more
core  

Arsenic in drinking water wells on the Bolivian high plain: field monitoring and effect of salinity on removal efficiency of iron-oxides-containing filters [PDF]

, 2010
In the rural areas around Oruro (Bolivia), untreated groundwater is used directly as drinking water. This research aimed to evaluate the general drinking water quality, with focus on arsenic (As) concentrations, based on analysis of 67 samples from about
De Deckere, E, Du Laing, Gijs, Montoya, Juan, Tack, Filip, Van den Bergh, Kenneth   +4 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Urine metabolomic characteristics of people exposed to hexavalent chromium in drinking water

Ecotoxicology and Environmental Safety
This study investigated the toxicological mechanisms of hexavalent chromium (Cr(VI)) exposure on human health by analyzing the urinary metabolomics of residents exposed to Cr(VI) through drinking water.
Tao Yanan, Hu Miaomiao, Xia Yunting, Peng Fangda, Xiong Chuanlong, Ding Chunguang   +5 more
doaj   +1 more source

Fluoride in Drinking Water: a Comparison Between Two Areas in Selangor and Kuala Lumpur, Malaysia [PDF]

, 2017
Background: The fluoridation of drinking water is a systemic approach by health authorities to eradicate dental-related problems among the population at large.
Abidin, Z. (Zaenal), MS, N. S. (Nurul), MS, S. (Shaharuddin), Z, A. S. (Ahmad)   +3 more
core  

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Organophosphate esters in reservoir water from a metropolitan city in the Guangdong-Hong Kong-Macao Greater Bay Area, China, and their ecological risk

Emerging Contaminants
Organophosphate esters (OPEs) are emerging flame retardants widely used in products such as furniture, electronic equipment, construction, and plastics. It has been demonstrated that OPEs are harmful to humans and aquatic organisms, thus posing a threat ...
Yi Huang, Yiming Ge, Chenglin Li, Linshen Xie, Xiujuan Qi, Pu Ye, Xixiang Guo, Chen Deng, Rong Hu, Jinling Wang, Yihong Liu, Bei Wang, Tingting Zhu, Shaoyou Lu   +13 more
doaj   +1 more source