Results 161 to 170 of about 69,370 (303)

Biodegradable Organic Matter in Drinking Water Treatment and Distribution

open access: yes, 2005
Biodegradable Organic Matter in Drinking Water Treatment and Distribution is a comprehensive reference on biodegradable organic matter (BOM) from source to tap and its relevance to full-scale water systems.
Laurent, Patrick   +2 more
core  

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

open access: yesAdvanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu   +13 more
wiley   +1 more source

Biofilms in the potable water distribution network [PDF]

open access: yes
The roles of vegetative dormancy and attachment to surfaces in the survival and growth of bacteria in potable water systems were investigated. Species present in the water were identified following isolation or direct observation of static batch ...
Jakubovics, Nicholas S.
core  

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang   +12 more
wiley   +1 more source

On Consumers' Attitudes and Willingness to Pay for Improved Drinking Water Quality and Infrastructure

open access: yes
Replaced with revised version of paper 07/23/09.willingness to pay, risk perceptions, water infrastructure, simultaneous equation model, Environmental Economics and Policy,
Mykerezi, Elton   +2 more
core   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

open access: yesAdvanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen   +14 more
wiley   +1 more source

Decision Support System for Evaluating Rural Water Supply Infrastructure Scenarios

open access: yes
This paper seeks to develop a methodology that will be useful for rural water districts in assessing the future of their water systems infrastructure.
Whitacre, Brian E.   +2 more
core   +1 more source

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