Results 91 to 100 of about 3,346 (228)

Adiponectin promotes AMPA receptor trafficking and enhances excitatory synaptic transmission at hippocampal synapses via AMP‐activated protein kinase signalling

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Peripherally derived adiponectin crosses the blood–brain barrier and targets severa0l brain regions. Adiponectin receptors are highly expressed in the hippocampus, and play a pro‐cognitive role as adiponectin markedly influences the functioning of hippocampal synapses.
Alexandra Soca   +4 more
wiley   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys   +14 more
wiley   +1 more source

Freeze-dried B.C.G [PDF]

open access: yesArchives of Disease in Childhood, 1960
J, LORBER, P C, MENNEER
openaire   +2 more sources

Aqueous Humour Cytokines as Predictors of Axial Elongation in High Myopia: A 2‐Year Longitudinal Cohort Study

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate the predictive value of aqueous humour cytokines for axial elongation. Methods This was a prospective longitudinal observational study. 72 high myopia patients (72 eyes) who received implantable collamer lens (ICL) implantation surgery with at least 2 years of follow‐up were included.
Lihui Meng   +4 more
wiley   +1 more source

The Effect of Mine‐Related Groundwater Use and Management on Surface Water in the Middle Humboldt River Basin

open access: yesGroundwater, EarlyView.
Abstract The Humboldt River, in Northern Nevada, USA, is a source of water for agricultural, municipal, and industrial uses. Mining has been active in Nevada since the 1800s. The recognition that groundwater withdrawal for many purposes—including mining—has the potential to deplete streamflow has prompted studies of the Humboldt River Basin.
Matthew Tonkin   +2 more
wiley   +1 more source

Mapping of C5‐Blocking Monoclonal Antibodies Reveals New C5 Inhibitory Epitopes and Novel Modes of C5 Inhibition

open access: yesImmunology, EarlyView.
We identify four distinct C5 inhibitory epitopes, including two novel antibodies that selectively block membrane attack complex (MAC) assembly while preserving C5 cleavage and C5a generation. These findings establish selective MAC inhibition as a new therapeutic strategy for complement‐mediated diseases.
Rebekah Sian Cooke   +5 more
wiley   +1 more source

DRIED VACCINE

open access: yesAmerican Journal of Public Health, 1912
W F, Elgin, J G, George
openaire   +3 more sources

Mini social cognition and emotional assessment: Diagnostic performance and neural correlates in behavioural‐variant frontotemporal dementia

open access: yesJournal of Neuropsychology, EarlyView.
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu   +27 more
wiley   +1 more source

DRI Factsheet No 5: About DRI Membership

open access: yes, 2017
Outline of the membership model of DRI and the different administrative roles.
openaire   +1 more source

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